Chocolate Cow2
Well-known member
Current price for 25 individual doses at Jeffers is $62.09. I put 10 boxes in my shopping cart and there was no price break for a larger purchase.
Chocolate Cow2 said:Current price for 25 individual doses at Jeffers is $62.09. I put 10 boxes in my shopping cart and there was no price break for a larger purchase.
Locally?I bought 2 25 dose boxes last week for $48 each.
That's my protocol as well.The 85% response is why I give BS5L5HB 30 days apart on my calves. You have to give a booster for the BRSV, so instead of sticking a needle in them for 1 thing, I hit them with the full vaccine.
Chocolate Cow2 said:Ron said he bought Inforce3 from Jeffers for $43.69- 25 single dose. I checked their site and it's $62.09 for 25 single dose. Maybe it's gone up since he bought last, idk. That's a big price difference. I put 10 boxes in my cart to see if there was a price break for buying more. There isn't. 1 box of 25 or 10 boxes, it's still $62.09 a box.
Yes the $48 is at the TN co-op and my local feed store. And not worrying about the shipping is good to.76 Bar said:Locally?I bought 2 25 dose boxes last week for $48 each.
That's my protocol as well.The 85% response is why I give BS5L5HB 30 days apart on my calves. You have to give a booster for the BRSV, so instead of sticking a needle in them for 1 thing, I hit them with the full vaccine.
Jeanne - Simme Valley said:Agreed - I am sold on the product. Like I said above, I also use it as a go-to if a calf is going to be stressed or acts a little puny. I can't explain it as fancy as BrightRaven, but it kicks in their own immune system & they fight off what might get them or is getting them. Ron's statement: " Inforce 3 initiates an immune response - the vaccine acts as antigens and the calf produces the antibodies." All I know, is it really works without giving antibiotics - now this is only if they are a "little" puny - not blown out sick.
Bright Raven said:Jeanne - Simme Valley said:Agreed - I am sold on the product. Like I said above, I also use it as a go-to if a calf is going to be stressed or acts a little puny. I can't explain it as fancy as BrightRaven, but it kicks in their own immune system & they fight off what might get them or is getting them. Ron's statement: " Inforce 3 initiates an immune response - the vaccine acts as antigens and the calf produces the antibodies." All I know, is it really works without giving antibiotics - now this is only if they are a "little" puny - not blown out sick.
May I add this in simple words? A vaccine contains parts (or the whole) of the germ (pathogen). An example would be proteins from the germ. These parts are the "antigens". The immune system of the calf responds to these antigens by producing "antibodies". These antibodies remain in the body to act as "identifiers". So when the calf is exposed to the real pathogen, the antibodies identify the pathogen and "tell" the leukocytes to go to war against the pathogen.
This process can be initiated by a vaccine or the real live pathogen during an infection.
In the case of colostrum, it is, so to speak, a "borrowed" immunity. The calf borrows the immunity from mom. The calf "borrows" mom's antibodies. The problem with this immunity is that at the end of the "loan period", it is no good. This is when people refer to a calf having a "crash of the immune system". What they are finding out is that all along this period, the calf's immune system is actually at work developing its own immune response.
Btw: immunity can be against the organism or against the toxin the organism secretes.
Jeanne - Simme Valley said:Still a lot of words. All I know, is vet explained it "kicks in" their immune response and they fight off current exposure to bugs. It is designed to build immunities to IBR PI3 and BRSV and that may be what I am warding off during stress, but it sure seems to help keep them healthy during stress and it also helps if they are a little under the weather (not running a fever).
Ron, I like your explanation of colostrum. "borrowed" immunities LOL. that's a good & simple way to put it.
Silver said:It's been my understanding that it's a waste of medicine to vaccinate with Covexine and similar until calves are several weeks old. If the cows are vaccinated the calves should receive passive immunity via colostrum of their vaccinated mothers to reduce clostridial diseases. Passive immunity to prerfringens from colostrum should last up to 8-12 weeks.
Inforce 3 can be taken advantage of from day one.
Someone can correct me if I'm wrong.
Silver said:It's been my understanding that it's a waste of medicine to vaccinate with Covexine and similar until calves are several weeks old. If the cows are vaccinated the calves should receive passive immunity via colostrum of their vaccinated mothers to reduce clostridial diseases. Passive immunity to prerfringens from colostrum should last up to 8-12 weeks.
Inforce 3 can be taken advantage of from day one.
Someone can correct me if I'm wrong.
Buck Randall said:Silver said:It's been my understanding that it's a waste of medicine to vaccinate with Covexine and similar until calves are several weeks old. If the cows are vaccinated the calves should receive passive immunity via colostrum of their vaccinated mothers to reduce clostridial diseases. Passive immunity to prerfringens from colostrum should last up to 8-12 weeks.
Inforce 3 can be taken advantage of from day one.
Someone can correct me if I'm wrong.
You're generally correct. The vaccine would potentially have some benefit to calves who did not get protective immunity from colostrum (10-20% in most herds). The problem with most injectable vaccines is that they are unnecessarily hard on calves at that age. Newer research in dairy calves has shown that vaccinating with most injectable vaccines is actually harmful to very young calves, as it produces more stress than it's worth. The one exception to this was C/D & T vaccine, which didn't set calves back. I would definitely avoid using 7 or 8 way clostridials or injectable modified live respiratory vaccines in newborn calves.