Most used gun I have is a Ruger 22/45 pistol with a 5.5 bull barrel in stainless. Takes care of about anything my cur either tree's or has cornered in "his" yard.
My primary CCW is a Smith 3913 I've had since around 1990, it was my BUG (back up gun) when I was a police officer.
Got a third generation Glock 17 that is a fun gun to shoot and I'd trust my life to it. Bought a couple 33 round magazines for it that really makes it a hoot but usually the 17+1 in the pipe is more than enough.
Varmint hunting, I use a Colt AR-15 (.223). Got 2 uppers for it. One short barrel (16 inch) with carry handle and peep sight and scope with lighted recticle, and long distance shooting I use a 20 inch H-Bar with the front sight post milled off, Hogue overmold hand guard, flat top receiver, 3-9 Variable power scope.
Bird hunting from quail to turkey, Benelli M-2 in Realtree HD camo with a 26 inch barrel. I put a 4 shot magazine extension tube on it and when it's not bird season I change the barrel to an 18.5 inch blued one off an M-1/Super 90 and it makes for one heck of a HD/tactical rig. Real close to what the Marines are using right now (Benelli M-4).
Anything bigger than a coyote I use a Remington 700, 30-06, BDL, DM, in stainless.
Got a few others I don't ever use including one "safe queen". It's a Belgium Browning Broadway Trap. Dad gave it to me, he's got more 25/25, 50/50, and even 100/100 patches than I can count he got using it but it's too pretty for me to use out here. Might take it to a trap range one of these days but otherwise she's fine in the safe.
J