Cows have not always been the way they are now. Domestication has greatly altered them, that is how we got the different breeds. Holsteins were not created that way, they were bred that way.
The point is that if some cows can sustain multiple births and calves then it should be possible to breed strains of cattle that regularly have multiple births, just as dairymen have bred for 30,000 + pounds of milk.
Increasing the fecundity of cattle would do more to increase profitability than all the minor cosmetic improvements we have focusewd on in the past. The largest expense to producing a calf is maintaining the mother. Even if the individual calves mature a hundred pounds or so lighter than usual we would still be far ahead in profit.
In 2006 we had an angus give birth to twins that turned out to be the largest in the herd (30 cows). She never needed any special attention. Ironically she and her 600+ pound calves were killed by a single lightning strike. Shows that there are lots of ways other than birthing difficulties, nursing problems, etc. to lose cattle but we learn to live with them and find solutions. So why, if there will be initial problems developing multiple birthing cows, do people throw up their hands and say no way. Good thing the people who developed treatments for the different diseases didn't take the same stance when they hit a rough spot.