Ergovaline, Ergonovine, and some of the other alkaloids produced by the 'bad' endophyte in some fescues, like 'dirty' KY-31, can cause agalactia (no milk); one of their actions is to decrease or prevent secretion of the prolactin hormone which 'primes' the udder for milk production.
Some years, growing conditions are worse than others for endophyte and toxic alkaloid production - and standing forages or hay - particularly if seedheads are a significant component - can cause problems with 'fescue foot', sloughed tailheads, and, yes, no milk.
Have a friend and former co-worker who's currently seeing numerous cows with fescue foot and sloughed tailswitches in his herd; feeding only home-grown fescue hay. I'll bet a Coke that it's high endophyte/ergovaline levels in the hay (pastures are kaput) that are causing the problem, and have recommended that he supplement with some corn, CGF, SHP, DDG etc., in order to dilute and offset the effects. Saw a presentation recently that referenced a 2007 J.An.Sci. publication on using a commercially-available yeast cell wall derivative that, as a feed supplement, looks to have some promise in offsetting the effects of endophyte alkaloids in fescue straw/hay.
Here's the article:
http://jas.fass.org/cgi/reprint/85/10/2596
It's an extreme case, but about 18 years ago, there was a producer in my area who'd gotten hold of some fescue screenings(the junk left over after KY-31 fescue seed was combined and cleaned), and was feeding them as a supplement - nutritional analysis showed a relatively high crude protein level, and they were 'cheap' (free). Or, at least, he
thought they were.
Several hundred head of stocker cattle lost ears, tails, feet; herd of registered Brangus cows calved out with no udder development and calves starved to death. Ergovaline levels in the screenings was 'off the chart'. It was a tremendous train wreck, and a big lawsuit ensued.