Is the bull out with her? If so, do you know that he's fertile?
Have you preg-checked her to see if she's bred or not? I've had bred cows stand - have had two heifers in the past couple of years that we AIed on a
'return to estrus', that calved to their first AI service. GnRH shouldn't hurt, if she is, but if you follow with a dose of Lute/Estrumate, you could terminate the pregnancy.
Lepto hardjo-bovis infection can cause repeated early embryonic death and return to estrus. Same for Trich.