newbie":1i0gum6o said:
Thanks Alice. I ended up with Microtel as my buddy said it would be easier on the young calf. Susie drank a little this morning. Gave her the med around 5 and am supposed to give the rest of the Microtel in two days. Temp is still 103. She is laying down her her shed now while the younger Friday frolicks around. He also gave me a vitamin paste that should increase her appetite. They must of gotten a draft when it was really windy the other night. I hear Friday coughing but she is still full of be nice and vinegar. Will take her temp tonight after she is a little more tired.
If you are using Micotil - you be sure you do not stick yourself with it.
-----------------------------------
Read and heed:
Health Canada and Elanco Animal Health have identified a risk of potential fatal outcomes upon accidental self-injection of Micotil®. Elanco Animal Health has been working closely with the Veterinary Drugs Directorate to ensure that the proper handling and administration of Micotil® is reinforced. Since the Micotil® approval in 1992, there have been reported cases to the Canadian Poison Control Centres of adverse human reactions to Micotil. The route of exposure in the majority of cases is by accidental puncture / scratch / injection, with oral ingestion, face/eyes and dermal exposure occurring infrequently. Micotil® is a macrolide veterinary antibiotic with cardiotoxic side-effects. It causes negative inotropy and in cases of accidental human exposure, requires constant cardiovascular system monitoring. Accidental needle puncture of less than 1 mL usually results in nothing more than edema and/or pain at the site of injection, however, higher doses can result in fatalities. In Canada, none of these reports have been of a serious nature, however, in the US, accidental injection of a full dose for cattle has been associated with fatalities. As these reactions are serious, the product monograph has been changed to reflect this new safety information.
HUMAN WARNING: Not for human use. Human injection has been associated with fatalities. Do not use in automatically powered syringes. Exercise caution to avoid accidental self-injection. In case of human injection, consult a physician immediately and apply ice to injection site. For emergency medical information call 1-416-813-5900.
NOTE TO THE PHYSICIAN: The cardiovascular system is the target of toxicity and should be monitored closely. This antibiotic persists in tissues for several days. Apply ice to injection site and provide supportive treatment. Epinephrine potentiated lethality of Micotil in pigs. Dobutamine partially offset the negative inotropic effects induced by Micotil in dogs. -adrenergic antagonists, such as propranolol, exacerbated the negative inotropy of Micotil-induced tachycardia in dogs.
As a veterinarian, you play a key role in protecting clients from accidental exposure or self-injection. We encourage you to continue to diligently train your clinic staff regarding safe handling procedures and take steps to ensure they are providing appropriate information to clients when dispensing Micotil®. This notice serves to remind the veterinary community of caution when handling any veterinary drug as well as to inform you of the changes to the monograph. Below is a reminder of proper handling of Micotil®.
Proper Injectable Handling Procedures
Store Micotil® in a safe location
Read, understand and follow all label use directions
For subcutaneous use in cattle
Use a 1/2 " to 5/8" 18- to 16-gauge needle
Keep a protective cover on needles until ready to use
Never carry loaded syringe in pocket or clothing
Wash hands thoroughly with soap and water after handling
Proper Injectable Administration Procedures
Properly restrain animals prior to administering Micotil®
With a single hand on the syringe, insert the needle subcutaneously, at a top-down angle, while avoiding penetration of underlying muscle
Administer a single subcutaneous dose of 1.5 mL of Micotil® per 100 lbs of body weight
Ensure proper disposal of sharp needles and syringes
Reporting rates determined on the basis of spontaneously reported post-marketing adverse events are generally presumed to underestimate the risks associated with drug treatments. The identification, characterization, and management of marketed health product-related adverse events are dependent on the active participation of veterinarians in adverse drug reaction reporting programmes. Any occurrences of human exposures or other serious and/or unexpected adverse events in animals receiving Micotil® should be reported to Elanco Animal Health using the following contact information:
Elanco Animal Health
Division of Eli Lilly Canada Inc.
Research Park Centre
150 Research Park Lane, Suite 120
Guelph, ON N1G 4T2
Tel: 1-800-265-5475 or Fax: (519) 821-7831
Sincerely yours,
Paul Dick, B.Sc., D.V.M., M.Sc.
Manager, Research and Development and Technical Service
----------------------------------------
I do not know the person but he lived not far from our home in Saskatchewan - he is no longer among the living because of this drug. Yearling jumped and he stuck himself - and died.
Lots of folks who handle drugs and cows together - sooner or later will put some drug in their body.
A good drug but I leave it on the counter at the store.
Bez>
with a needle that had nuflor in it...I'm still here...altho I didn't think I'd ever get that taste outta my mouth or the feeling back in my tongue.
