I don't know??? :???: Some that have an eye draining clear up in a day or two,some have the eye just start to have a little grey then clear up and others have the eye turn grey so bad they can't see out of it.If the eye is turning grey I've been giving a shot of LA300 and that has worked well but one cow had two rounds of LA300 because both eyes were grey and now her eyes are back to normal.I tried the Vetericyn Pinkeye spray today on two cows and two calves that had an eye draining so I'll check on them in the morning.