One point that is commonly misunderstood by producers... cattle do not become 'resistant' to any particular dewormer or class of dewormers, no matter how many times you administer them... the WORMS do.
When you deworm an animal (or the entire herd), the dewormer you use will kill all worms in that animal that are susceptible to it. But if there are any worms in that animal that are resistant to that class of dewormer, they become the 'parents' for the next generation of infective larvae that will develop out there on the pasture to infect grazing animals, so that next generation of infective worm larvae will predominantly be 'resistant' to all members of that class.
If, by your actions, you select for a population of worms that are resistant to ivermectin... they are also resistant to doramectin(Dectomax) and moxidectin(Cydectin). If they are resistant to fenbendazole(Panacur/Safeguard), they are also resistant to albendazole(Valbazen), oxfendazole(Synanthic), etc. And... it appears that once you've selected for worm populations resistant to those two classes of anthelminthics, that resistance is 'forever'.
So... we're trying to get producers to try to preserve the 'refugia' - that portion of the worm population that is still susceptible. MOST adult cattle do not need to be dewormed; certainly, there are individuals who do not develop the normal resilience to infection, or may be immunosuppressed due to malnutrition, etc., but most adults have few if any worms. Ideally, you would run fecal exams and only deworm those showing heavy infections, but we know that is not a 'real-world' approach. So, a better tactic is, IF you think, based on here body condition, that a cow may be heavily parasitized, only deworm those individual cows that you think 'need' it. If you're one of those who think you HAVE to deworm the entire herd... at least consider not deworming 10-20% of the adult animals in the herd... this leaves them as a potential source of 'susceptible' worms that won't be introducing 'resistance' genes into the breeding population.
Obviously, if you're in a liver fluke area... you're gonna have to deworm 'everybody' with an anthelminthic effective against flukes.
Final word from me today: You can feed your way through a worm problem. You can't deworm your way out of a nutritional deficiency.