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Selecting & Linebreeding Homozygous Traits -- The New Way?
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<blockquote data-quote="HerefordSire" data-source="post: 616332" data-attributes="member: 4437"><p><em>Imagine selecting, before birth and before ET, from a group of bovine embryos prior to implanting the best ones into recipients, if we could evaluate the best genetic combinations before implanting. One could bypass, the homozygous and heterozygous CCS, Dwarf, and other alleles, and capture all the positive homozygous alleles to increase the likelihood of producing the best animals of all the flush material invested in. The ethical question may be what we will do with the remaining embryos. Should we discard them or sell them by informing the user of the potential consequences?</em></p><p></p><p>Baby selected to be free of cancer gene</p><p></p><p>The first UK baby genetically selected to be free of a form of breast cancer - caused by a gene called BRCA1 - has been born in London. Doctors said three generations of women in the baby girl's family had suffered from breast and ovarian cancer in their 20s, and this child will be free of that risk. </p><p>.</p><p>.</p><p>.</p><p>The parents underwent IVF, and the resulting embryos were screened with preimplantation genetic diagnosis (PGD), where a small number of cells are removed and tested. Only embryos free of the BRCA1 gene were implanted</p><p>.</p><p>.</p><p>.</p><p>Carriers of BRCA1 have an 80% chance of developing breast cancer and a 60% chance of developing ovarian cancer.</p><p></p><p><a href="http://www.newscientist.com/blogs/shortsharpscience/2009/01/is-this-the-start-of-designer.html" target="_blank">http://www.newscientist.com/blogs/short ... igner.html</a></p></blockquote><p></p>
[QUOTE="HerefordSire, post: 616332, member: 4437"] [i]Imagine selecting, before birth and before ET, from a group of bovine embryos prior to implanting the best ones into recipients, if we could evaluate the best genetic combinations before implanting. One could bypass, the homozygous and heterozygous CCS, Dwarf, and other alleles, and capture all the positive homozygous alleles to increase the likelihood of producing the best animals of all the flush material invested in. The ethical question may be what we will do with the remaining embryos. Should we discard them or sell them by informing the user of the potential consequences?[/i] Baby selected to be free of cancer gene The first UK baby genetically selected to be free of a form of breast cancer - caused by a gene called BRCA1 - has been born in London. Doctors said three generations of women in the baby girl's family had suffered from breast and ovarian cancer in their 20s, and this child will be free of that risk. . . . The parents underwent IVF, and the resulting embryos were screened with preimplantation genetic diagnosis (PGD), where a small number of cells are removed and tested. Only embryos free of the BRCA1 gene were implanted . . . Carriers of BRCA1 have an 80% chance of developing breast cancer and a 60% chance of developing ovarian cancer. [url=http://www.newscientist.com/blogs/shortsharpscience/2009/01/is-this-the-start-of-designer.html]http://www.newscientist.com/blogs/short ... igner.html[/url] [/QUOTE]
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