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NCBA, R-CALF, COOL, USDA (No Politics!)
Ranchers in Texas Need to Pay Close Attention to CWD TSE Prion
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<blockquote data-quote="flounder" data-source="post: 1850391" data-attributes="member: 3519"><p>ARS RESEARCH UPDATE ANNUAL REPORT 2023</p><p></p><p>Elucidating the Pathobiology and Transmission of Transmissible Spongiform Encephalopathies</p><p></p><p>[URL unfurl="true"]https://www.ars.usda.gov/research/project/?accnNo=440677&fy=2023[/URL]</p><p></p><p><strong>Title:</strong> Transmission of raccoon passaged chronic wasting disease agent to white-tailed deer</p><p></p><p><strong>Publication Date:</strong> 7/20/2022</p><p></p><p>[URL unfurl="true"]https://www.ars.usda.gov/research/publications/publication/?seqNo115=394410[/URL]</p><p></p><p>[URL unfurl="true"]https://www.ars.usda.gov/research/publications/publication/?seqNo115=394109[/URL]</p><p></p><p><strong>Title:</strong> Disease-associated prion protein detected in lymphoid tissues from pigs challenged with the agent of chronic wasting disease</p><p></p><p><strong>Publication Acceptance Date:</strong> 3/15/2017</p><p></p><p>Conclusions: This study demonstrates that PrPSc accumulates in lymphoid tissues from pigs challenged intracranially or orally with the CWD agent, and can be detected as early as 4 months after challenge. CWD-infected pigs rarely develop clinical disease and if they do, they do so after a long incubation period. This raises the possibility that CWD-infected pigs could shed prions into their environment long before they develop clinical disease. Furthermore, lymphoid tissues from CWD-infected pigs could present a potential source of CWD infectivity in the animal and human food chains.</p><p></p><p>[URL unfurl="true"]https://www.ars.usda.gov/research/publications/publication/?seqNo115=337105[/URL]</p><p></p><p>Two Hunters from the Same Lodge Afflicted with Sporadic CJD: Is Chronic Wasting Disease to Blame?</p><p></p><p>(P7-13.002) Jonathan Trout, Matthew Roberts, Michel Tabet, Eithan Kotkowski, and Sarah HornAUTHORS INFO & AFFILIATIONS April 9, 2024 issue 102 (17_supplement_1) <a href="https://doi.org/10.1212/WNL.0000000000204407" target="_blank">https://doi.org/10.1212/WNL.0000000000204407</a></p><p></p><p><a href="https://www.neurology.org/doi/abs/10.1212/WNL.0000000000204407" target="_blank">https://www.neurology.org/doi/abs/10.1212/WNL.0000000000204407</a></p><p></p><p>TUESDAY, MAY 11, 2021</p><p></p><p>A Unique Presentation of Creutzfeldt-Jakob Disease in a Patient Consuming Deer Antler Velvet</p><p></p><p>Conclusion</p><p></p><p>''We believe that our patient's case of CJD is highly suspicious for cervid etiology given the circumstances of the case as well as the strong evidence of plausibility reported in published literature. This is the first known case of CJD in a patient who had consumed deer antler velvet. Despite the confirmed diagnosis of CJD, a causal relationship between the patient's disease and his consumption of deer antler velvet cannot be definitively concluded.''</p><p></p><p><a href="https://thescipub.com/pdf/ajidsp.2021.43.48.pdf" target="_blank">https://thescipub.com/pdf/ajidsp.2021.43.48.pdf</a></p><p></p><p>Texas CWD 2024</p><p></p><p>As noted previously in this preamble, the department has been engaged in a long-term effort to stem the spread of CWD; however, by 2021 it was apparent that more robust measures were warranted because CWD was still being detected in additional deer breeding facilities, as well as on multiple release sites associated with CWD-positive deer breeding facilities. The commission adopted those rules, which require higher rates of testing, ante-mortem (live-animal) testing of breeder deer prior to release, and enhanced recordkeeping and reporting measures, in December of 2021 (46 TexReg 8724).</p><p> Following the implementation of more efficacious testing requirements, an unprecedented increase in CWD detections occurred. Since 2021, CWD has been detected in 22 deer breeding facilities, two release sites associated with CWD-positive deer breeding facilities, and two free-ranging deer in areas where CWD had not been previously detected. Department records indicate that within the last five years those breeding facilities transferred over 7,000 deer to other breeding facilities, release sites, and Deer Management Permit (DMP) sites. All those locations are therefore directly connected to the CWD-positive facilities and are subsequently of epidemiological concern. Additionally, approximately 287 deer breeding facilities received deer from one or more of the directly connected breeding facilities, which means those facilities (referred to as "Tier 1" facilities) are indirectly connected to the positive facilities and are also of epidemiological concern because they have received exposed deer that were in a trace-out breeding facility.</p><p>Because of this rapid explosion in epidemiological linkages between deer breeding facilities and associated release sites, the department became concerned about the excessive numbers of deer breeders continuing to be affected by inter-facility transfers, and subsequently determined that additional testing measures could increase the probability of detecting CWD in breeding facilities where it exists before it could be spread to additional breeding facilities and associated release sites.</p><p></p><p>Learn more and comment online through 5 p.m. May 22, 2024.</p><p></p><p><a href="https://tpwd.texas.gov/business/feedback/public_comment/proposals/202405_cwd_rules.phtml" target="_blank">https://tpwd.texas.gov/business/feedback/public_comment/proposals/202405_cwd_rules.phtml</a></p><p></p><p>THURSDAY, APRIL 25, 2024 </p><p></p><p>TAHC 2 does tested positive and additional testing resulted in 3 subsequent CWD detections Edwards County Deer Breeding Facility </p><p></p><p><a href="https://chronic-wasting-disease.blogspot.com/2024/04/tahc-2-does-tested-positive-and.html" target="_blank">Chronic Wasting Disease: TAHC 2 does tested positive and additional testing resulted in 3 subsequent CWD detections Edwards County Deer Breeding Facility</a></p><p></p><p>terry</p><p></p><p><a href="https://chronic-wasting-disease.blogspot.com/2024/04/tahc-2-does-tested-positive-and.html" target="_blank"> <table style='width: 100%'><tr><td><table style='width: 100%'><tr><td><table style='width: 100%'><tr><td><table style='width: 100%'><tr><td></td><td></td></tr></table></td></tr></table></td></tr><tr><td><div style="text-align: center"><table style='width: 100%'><tr><td></td><td> [h2]Chronic Wasting Disease: TAHC 2 does tested positive and additional test...[/h2] </td></tr></table></div> </td></tr></table></td></tr></table><p></a></p><p></p><p></p><p>Terry S. Singeltary Sr.</p></blockquote><p></p>
[QUOTE="flounder, post: 1850391, member: 3519"] ARS RESEARCH UPDATE ANNUAL REPORT 2023 Elucidating the Pathobiology and Transmission of Transmissible Spongiform Encephalopathies [URL unfurl="true"]https://www.ars.usda.gov/research/project/?accnNo=440677&fy=2023[/URL] [B]Title:[/B] Transmission of raccoon passaged chronic wasting disease agent to white-tailed deer [B]Publication Date:[/B] 7/20/2022 [URL unfurl="true"]https://www.ars.usda.gov/research/publications/publication/?seqNo115=394410[/URL] [URL unfurl="true"]https://www.ars.usda.gov/research/publications/publication/?seqNo115=394109[/URL] [B]Title:[/B] Disease-associated prion protein detected in lymphoid tissues from pigs challenged with the agent of chronic wasting disease [B]Publication Acceptance Date:[/B] 3/15/2017 Conclusions: This study demonstrates that PrPSc accumulates in lymphoid tissues from pigs challenged intracranially or orally with the CWD agent, and can be detected as early as 4 months after challenge. CWD-infected pigs rarely develop clinical disease and if they do, they do so after a long incubation period. This raises the possibility that CWD-infected pigs could shed prions into their environment long before they develop clinical disease. Furthermore, lymphoid tissues from CWD-infected pigs could present a potential source of CWD infectivity in the animal and human food chains. [URL unfurl="true"]https://www.ars.usda.gov/research/publications/publication/?seqNo115=337105[/URL] Two Hunters from the Same Lodge Afflicted with Sporadic CJD: Is Chronic Wasting Disease to Blame? (P7-13.002) Jonathan Trout, Matthew Roberts, Michel Tabet, Eithan Kotkowski, and Sarah HornAUTHORS INFO & AFFILIATIONS April 9, 2024 issue 102 (17_supplement_1) [URL]https://doi.org/10.1212/WNL.0000000000204407[/URL] [URL]https://www.neurology.org/doi/abs/10.1212/WNL.0000000000204407[/URL] TUESDAY, MAY 11, 2021 A Unique Presentation of Creutzfeldt-Jakob Disease in a Patient Consuming Deer Antler Velvet Conclusion ''We believe that our patient's case of CJD is highly suspicious for cervid etiology given the circumstances of the case as well as the strong evidence of plausibility reported in published literature. This is the first known case of CJD in a patient who had consumed deer antler velvet. Despite the confirmed diagnosis of CJD, a causal relationship between the patient's disease and his consumption of deer antler velvet cannot be definitively concluded.'' [URL]https://thescipub.com/pdf/ajidsp.2021.43.48.pdf[/URL] Texas CWD 2024 As noted previously in this preamble, the department has been engaged in a long-term effort to stem the spread of CWD; however, by 2021 it was apparent that more robust measures were warranted because CWD was still being detected in additional deer breeding facilities, as well as on multiple release sites associated with CWD-positive deer breeding facilities. The commission adopted those rules, which require higher rates of testing, ante-mortem (live-animal) testing of breeder deer prior to release, and enhanced recordkeeping and reporting measures, in December of 2021 (46 TexReg 8724). Following the implementation of more efficacious testing requirements, an unprecedented increase in CWD detections occurred. Since 2021, CWD has been detected in 22 deer breeding facilities, two release sites associated with CWD-positive deer breeding facilities, and two free-ranging deer in areas where CWD had not been previously detected. Department records indicate that within the last five years those breeding facilities transferred over 7,000 deer to other breeding facilities, release sites, and Deer Management Permit (DMP) sites. All those locations are therefore directly connected to the CWD-positive facilities and are subsequently of epidemiological concern. Additionally, approximately 287 deer breeding facilities received deer from one or more of the directly connected breeding facilities, which means those facilities (referred to as "Tier 1" facilities) are indirectly connected to the positive facilities and are also of epidemiological concern because they have received exposed deer that were in a trace-out breeding facility. Because of this rapid explosion in epidemiological linkages between deer breeding facilities and associated release sites, the department became concerned about the excessive numbers of deer breeders continuing to be affected by inter-facility transfers, and subsequently determined that additional testing measures could increase the probability of detecting CWD in breeding facilities where it exists before it could be spread to additional breeding facilities and associated release sites. Learn more and comment online through 5 p.m. May 22, 2024. [URL]https://tpwd.texas.gov/business/feedback/public_comment/proposals/202405_cwd_rules.phtml[/URL] THURSDAY, APRIL 25, 2024 TAHC 2 does tested positive and additional testing resulted in 3 subsequent CWD detections Edwards County Deer Breeding Facility [URL='https://chronic-wasting-disease.blogspot.com/2024/04/tahc-2-does-tested-positive-and.html']Chronic Wasting Disease: TAHC 2 does tested positive and additional testing resulted in 3 subsequent CWD detections Edwards County Deer Breeding Facility[/URL] terry [URL='https://chronic-wasting-disease.blogspot.com/2024/04/tahc-2-does-tested-positive-and.html'][TABLE] [TR] [TD][TABLE] [TR] [TD][TABLE] [TR] [TD][TABLE] [TR] [TD][/TD] [TD][/TD] [/TR] [/TABLE][/TD] [/TR] [/TABLE][/TD] [/TR] [TR] [TD][CENTER][TABLE] [TR] [TD][/TD] [TD][H2]Chronic Wasting Disease: TAHC 2 does tested positive and additional test...[/H2] [/TD] [/TR] [/TABLE][/CENTER][/TD] [/TR] [/TABLE][/TD] [/TR] [/TABLE][/URL] Terry S. Singeltary Sr. [/QUOTE]
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