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May 2007 Update on BSE Feed Enforcement, or the lack of
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<blockquote data-quote="flounder" data-source="post: 383838" data-attributes="member: 3519"><p>Subject: May 2007 Update on Feed Enforcement Activities to Limit the Spread</p><p>of BSE</p><p>Date: May 21, 2007 at 1:59 pm PST</p><p></p><p>greetings,</p><p></p><p></p><p>WOW, some feed ban. you would have thought by now the infamous August 4,</p><p>1997 mad cow feed ban would have taken place by now. from the mad cow feed</p><p>ban warning letter just several months ago, where 10,000,000 LBS of banned</p><p>material went out into commerce to be fed out again, I cannot imagine how</p><p>much more tainted product is out there from the looks of this latest report.</p><p>...terry</p><p></p><p></p><p>CVM Update</p><p>May 18, 2007</p><p></p><p>May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE</p><p></p><p>To help prevent the establishment and amplification of Bovine Spongiform</p><p>Encephalopathy (BSE) through feed in the United States, the Food and Drug</p><p>Administration (FDA) implemented a final rule that prohibits the use of most</p><p>mammalian protein in feeds for ruminant animals. This rule, Title 21 Part</p><p>589.2000 of the Code of Federal Regulations, here called the Ruminant Feed</p><p>Ban, became effective on August 4, 1997.</p><p></p><p>The following is an update on FDA enforcement activities regarding the</p><p>ruminant feed ban. FDA's Center for Veterinary Medicine (CVM) has assembled</p><p>data from the inspections that have been conducted AND whose final</p><p>inspection report has been recorded in the FDA's inspection database as of</p><p>May 12, 2007. As of May 12, 2007, FDA had received over 53,000 inspection</p><p>reports. The majority of these inspections (around 68%) were conducted by</p><p>State feed safety officials, with the remainder conducted by FDA officials.</p><p>Inspections conducted by FDA or State investigators are classified to</p><p>reflect the compliance status at the time of the inspection based upon the</p><p>objectionable conditions documented. These inspection conclusions are</p><p>reported as Official Action Indicated (OAI), Voluntary Action Indicated</p><p>(VAI), or No Action Indicated (NAI).</p><p></p><p>An OAI inspection classification occurs when significant objectionable</p><p>conditions or practices were found and regulatory sanctions are warranted in</p><p>order to address the establishment's lack of compliance with the regulation.</p><p>An example of an OAI inspection classification would be findings of</p><p>manufacturing procedures insufficient to ensure that ruminant feed is not</p><p>contaminated with prohibited material. Inspections classified with OAI</p><p>violations will be promptly re-inspected following the regulatory sanctions</p><p>to determine whether adequate corrective actions have been implemented.</p><p></p><p>A VAI inspection classification occurs when objectionable conditions or</p><p>practices were found that do not meet the threshold of regulatory</p><p>significance, but do warrant advisory actions to inform the establishment of</p><p>findings that should be voluntarily corrected. Inspections classified with</p><p>VAI violations are more technical violations of the Ruminant Feed Ban. These</p><p>include provisions such as minor recordkeeping lapses and conditions</p><p>involving non-ruminant feeds.</p><p></p><p>An NAI inspection classification occurs when no objectionable conditions or</p><p>practices were found during the inspection or the significance of the</p><p>documented objectionable conditions found does not justify further actions.</p><p></p><p>The results to date are reported here both by "segment of industry" and "in</p><p>total". NOTE – A single firm can operate as more than one firm type. As a</p><p>result, the categories of the different industry segments are not mutually</p><p>exclusive.</p><p></p><p>RENDERERS</p><p></p><p>These firms are the first to handle and process (i.e., render) animal</p><p>proteins and to send these processed materials to feed mills and/or protein</p><p>blenders for use as a feed ingredient.</p><p></p><p>Number of active firms whose initial inspection has been reported to FDA –</p><p>269</p><p></p><p>Number of active firms handling materials prohibited from use in ruminant</p><p>feed – 161 (60 % of those active firms inspected)</p><p></p><p>Of the 161 active firms handling prohibited materials, their most recent</p><p>inspection revealed that:</p><p></p><p>0 firms (0.0 %) were classified as OAI</p><p></p><p>4 firms (2.5 %) were classified as VAI</p><p></p><p>LICENSED FEED MILLS</p><p></p><p>FDA licenses these feed mills to produce medicated feed products. The</p><p>license is required to manufacture and distribute feed using certain potent</p><p>drug products, usually those requiring some pre-slaughter withdrawal time.</p><p>This licensing has nothing to do with handling prohibited materials under</p><p>the feed ban regulation. A medicated feed license from FDA is not required</p><p>to handle materials prohibited under the Ruminant Feed Ban.</p><p></p><p>Number of active firms whose initial inspection has been reported to FDA –</p><p>1,074</p><p></p><p>Number of active firms handling materials prohibited from use in ruminant</p><p>feed – 444 (41 % of those active firms inspected)</p><p></p><p>Of the 444 active firms handling prohibited materials, their most recent</p><p>inspection revealed that:</p><p></p><p>0 firms (0.0 %) were classified as OAI</p><p></p><p>5 firms (1.1 %) were classified as VAI</p><p></p><p>FEED MILLS NOT LICENSED BY FDA</p><p></p><p>These feed mills are not licensed by the FDA to produce medicated feeds.</p><p></p><p>Number of active firms whose initial inspection has been reported to FDA –</p><p>5,183</p><p></p><p>Number of active firms handling materials prohibited from use in ruminant</p><p>feed – 2,391 (46 % of those active firms inspected)</p><p></p><p>Of the 2,391 active firms handling prohibited materials, their most recent</p><p>inspection revealed that:</p><p></p><p>3 firms (0.1 %) were classified as OAI</p><p></p><p>56 firms (2.3 %) were classified as VAI</p><p></p><p>PROTEIN BLENDERS</p><p></p><p>These firms blend rendered animal protein for the purpose of producing</p><p>quality feed ingredients that will be used by feed mills.</p><p></p><p>Number of active firms whose initial inspection has been reported to FDA –</p><p>386</p><p></p><p>Number of active firms handling materials prohibited from use in ruminant</p><p>feed – 183 (47% of those active firms inspected)</p><p></p><p>Of the 183 active firms handling prohibited materials, their most recent</p><p>inspection revealed that:</p><p></p><p>1 firm (0.5 %) was classified as OAI</p><p></p><p>7 firms (3.8 %) were classified as VAI</p><p></p><p>RENDERERS, FEED MILLS, AND PROTEIN BLENDERS MANUFACTURING WITH PROHIBITED</p><p>MATERIAL</p><p></p><p>This category includes only those firms that actually use prohibited</p><p>material to manufacture, process, or blend animal feed or feed ingredients.</p><p></p><p>Total number of active renderers, feed mills, and protein blenders whose</p><p>initial inspection has been reported to FDA – 6,604</p><p></p><p>Number of active renderers, feed mills, and protein blenders processing with</p><p>prohibited materials – 497 (7.5 %)</p><p></p><p>Of the 497 active renderers, feed mills, and protein blenders processing</p><p>with prohibited materials, their most recent inspection revealed that:</p><p></p><p>2 firms (0.4 %) were classified as OAI</p><p></p><p>24 firms (4.8 %) were classified as VAI</p><p></p><p>OTHER FIRMS INSPECTED</p><p></p><p>Examples of such firms include ruminant feeders, on-farm mixers, pet food</p><p>manufacturers, animal feed salvagers, distributors, retailers, and animal</p><p>feed transporters.</p><p></p><p>Number of active firms whose initial inspection has been reported to FDA –</p><p>17,227</p><p></p><p>Number of active firms handling materials prohibited from use in ruminant</p><p>feed – 5,415 (31% of those active firms inspected)</p><p></p><p>Of the 5,415 active firms handling prohibited materials, their most recent</p><p>inspection revealed that:</p><p></p><p>2 firms (0.04 %) were classified as OAI</p><p></p><p>186 firms (3.4%) were classified as VAI</p><p></p><p>TOTAL FIRMS</p><p></p><p>Note that a single firm can be reported under more than one firm category;</p><p>therefore, the summation of the individual OAI/VAI firm categories will be</p><p>more than the actual total number of OAI/VAI firms, as presented below.</p><p></p><p>Number of active firms whose initial inspection has been reported to FDA –</p><p>19,705</p><p></p><p>Number of active firms handling materials prohibited from use in ruminant</p><p>feed – 6,146 (31 % of those active firms inspected)</p><p></p><p>Of the 6,146 active firms handling prohibited materials, their most recent</p><p>inspection revealed that:</p><p></p><p>3 firms (0.05 %) were classified as OAI</p><p></p><p>200 firms (3.3 %) were classified as VAI</p><p></p><p></p><p>----------------------------------------------------------------------------</p><p>----</p><p></p><p>Issued by:</p><p>FDA, Center for Veterinary Medicine,</p><p>Communications Staff, HFV-12</p><p>7519 Standish Place, Rockville, MD 20855</p><p>Telephone: (240) 276-9300 FAX: (240) 276-9115</p><p>Internet Web Site: <a href="http://www.fda.gov/cvm" target="_blank">http://www.fda.gov/cvm</a></p><p></p><p></p><p><a href="http://www.fda.gov/cvm/CVM_Updates/BSE0507.htm" target="_blank">http://www.fda.gov/cvm/CVM_Updates/BSE0507.htm</a></p><p></p><p></p><p>10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA</p><p>2007</p><p></p><p></p><p></p><p>Date: March 21, 2007 at 2:27 pm PST</p><p>RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II</p><p>___________________________________</p><p>PRODUCT</p><p>Bulk cattle feed made with recalled Darling's 85% Blood Meal, Flash Dried,</p><p>Recall # V-024-2007</p><p>CODE</p><p>Cattle feed delivered between 01/12/2007 and 01/26/2007</p><p>RECALLING FIRM/MANUFACTURER</p><p>Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007.</p><p>Firm initiated recall is ongoing.</p><p>REASON</p><p>Blood meal used to make cattle feed was recalled because it was</p><p>cross-contaminated with prohibited bovine meat and bone meal that had been</p><p>manufactured on common equipment and labeling did not bear cautionary BSE</p><p>statement.</p><p>VOLUME OF PRODUCT IN COMMERCE</p><p>42,090 lbs.</p><p>DISTRIBUTION</p><p>WI</p><p></p><p>___________________________________</p><p>PRODUCT</p><p>Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL</p><p>Prot-Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal,</p><p>TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY</p><p>Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST</p><p>POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI – 8# SPECIAL</p><p>DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J – PROTEIN/LACTATION, ROCK</p><p>CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC</p><p>MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY,</p><p>A-BYPASS ML W/SMARTA, Recall # V-025-2007</p><p>CODE</p><p>The firm does not utilize a code - only shipping documentation with</p><p>commodity and weights identified.</p><p>RECALLING FIRM/MANUFACTURER</p><p>Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm</p><p>initiated recall is complete.</p><p>REASON</p><p>Products manufactured from bulk feed containing blood meal that was cross</p><p>contaminated with prohibited meat and bone meal and the labeling did not</p><p>bear cautionary BSE statement.</p><p>VOLUME OF PRODUCT IN COMMERCE</p><p>9,997,976 lbs.</p><p>DISTRIBUTION</p><p>ID and NV</p><p></p><p>END OF ENFORCEMENT REPORT FOR MARCH 21, 2007</p><p></p><p></p><p><a href="http://www.fda.gov/bbs/topics/enforce/2007/ENF00996.html" target="_blank">http://www.fda.gov/bbs/topics/enforce/2 ... 00996.html</a></p><p></p><p>> May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE</p><p></p><p></p><p>what about BASE ???</p><p></p><p></p><p>USA MAD COW STRAIN MORE VIRULENT TO HUMANS THAN UK STRAIN</p><p></p><p>18 January 2007 - Draft minutes of the SEAC 95 meeting (426 KB) held on 7</p><p>December 2006 are now available.</p><p></p><p></p><p>snip...</p><p></p><p>64. A member noted that at the recent Neuroprion meeting, a study was</p><p>presented showing that in transgenic mice BSE passaged in sheep may be more</p><p>virulent and infectious to a wider range of species than bovine derived BSE.</p><p></p><p>Other work presented suggested that BSE and bovine amyloidotic spongiform</p><p>encephalopathy (BASE) MAY BE RELATED. A mutation had been identified in the</p><p>prion protein gene in an AMERICAN BASE CASE THAT WAS SIMILAR IN NATURE TO A</p><p>MUTATION FOUND IN CASES OF SPORADIC CJD.</p><p></p><p></p><p>snip...</p><p></p><p><a href="http://www.seac.gov.uk/minutes/95.pdf" target="_blank">http://www.seac.gov.uk/minutes/95.pdf</a></p><p></p><p></p><p>3:30 Transmission of the Italian Atypical BSE (BASE) in Humanized Mouse</p><p></p><p>Models Qingzhong Kong, Ph.D., Assistant Professor, Pathology, Case Western</p><p>Reserve</p><p>University</p><p></p><p>Bovine Amyloid Spongiform Encephalopathy (BASE) is an atypical BSE strain</p><p>discovered recently in Italy, and similar or different atypical BSE cases</p><p>were also reported in other countries. The infectivity and phenotypes of</p><p>these atypical BSE strains in humans are unknown. In collaboration with</p><p>Pierluigi Gambetti, as well as Maria Caramelli and her co-workers, we have</p><p>inoculated transgenic mice expressing human prion protein with brain</p><p>homogenates from BASE or BSE infected cattle. Our data shows that about half</p><p>of the BASE-inoculated mice became infected with an average incubation time</p><p>of about 19 months; in contrast, none of the BSE-inoculated mice appear to</p><p>be infected after more than 2 years.</p><p></p><p>***These results indicate that BASE is transmissible to humans and suggest</p><p>that BASE is more virulent than</p><p>classical BSE in humans.***</p><p></p><p></p><p>6:30 Close of Day One</p><p></p><p></p><p><a href="http://www.healthtech.com/2007/tse/day1.asp" target="_blank">http://www.healthtech.com/2007/tse/day1.asp</a></p><p></p><p></p><p>SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM</p><p>1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype</p><p>of 'UNKNOWN' strain growing. ...</p><p></p><p></p><p><a href="http://www.cjdsurveillance.com/resources-casereport.html" target="_blank">http://www.cjdsurveillance.com/resource ... eport.html</a></p><p></p><p>There is a growing number of human CJD cases, and they were presented last</p><p>week in San Francisco by Luigi Gambatti(?) from his CJD surveillance</p><p>collection.</p><p></p><p>He estimates that it may be up to 14 or 15 persons which display selectively</p><p>SPRPSC and practically no detected RPRPSC proteins.</p><p></p><p></p><p><a href="http://www.fda.gov/ohrms/dockets/ac/06/transcripts/1006-4240t1.htm" target="_blank">http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.htm</a></p><p></p><p></p><p><a href="http://www.fda.gov/ohrms/dockets/ac/06/transcripts/2006-4240t1.pdf" target="_blank">http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.pdf</a></p><p></p><p></p><p>TSS</p></blockquote><p></p>
[QUOTE="flounder, post: 383838, member: 3519"] Subject: May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE Date: May 21, 2007 at 1:59 pm PST greetings, WOW, some feed ban. you would have thought by now the infamous August 4, 1997 mad cow feed ban would have taken place by now. from the mad cow feed ban warning letter just several months ago, where 10,000,000 LBS of banned material went out into commerce to be fed out again, I cannot imagine how much more tainted product is out there from the looks of this latest report. ...terry CVM Update May 18, 2007 May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE To help prevent the establishment and amplification of Bovine Spongiform Encephalopathy (BSE) through feed in the United States, the Food and Drug Administration (FDA) implemented a final rule that prohibits the use of most mammalian protein in feeds for ruminant animals. This rule, Title 21 Part 589.2000 of the Code of Federal Regulations, here called the Ruminant Feed Ban, became effective on August 4, 1997. The following is an update on FDA enforcement activities regarding the ruminant feed ban. FDA's Center for Veterinary Medicine (CVM) has assembled data from the inspections that have been conducted AND whose final inspection report has been recorded in the FDA's inspection database as of May 12, 2007. As of May 12, 2007, FDA had received over 53,000 inspection reports. The majority of these inspections (around 68%) were conducted by State feed safety officials, with the remainder conducted by FDA officials. Inspections conducted by FDA or State investigators are classified to reflect the compliance status at the time of the inspection based upon the objectionable conditions documented. These inspection conclusions are reported as Official Action Indicated (OAI), Voluntary Action Indicated (VAI), or No Action Indicated (NAI). An OAI inspection classification occurs when significant objectionable conditions or practices were found and regulatory sanctions are warranted in order to address the establishment's lack of compliance with the regulation. An example of an OAI inspection classification would be findings of manufacturing procedures insufficient to ensure that ruminant feed is not contaminated with prohibited material. Inspections classified with OAI violations will be promptly re-inspected following the regulatory sanctions to determine whether adequate corrective actions have been implemented. A VAI inspection classification occurs when objectionable conditions or practices were found that do not meet the threshold of regulatory significance, but do warrant advisory actions to inform the establishment of findings that should be voluntarily corrected. Inspections classified with VAI violations are more technical violations of the Ruminant Feed Ban. These include provisions such as minor recordkeeping lapses and conditions involving non-ruminant feeds. An NAI inspection classification occurs when no objectionable conditions or practices were found during the inspection or the significance of the documented objectionable conditions found does not justify further actions. The results to date are reported here both by “segment of industry” and “in total”. NOTE – A single firm can operate as more than one firm type. As a result, the categories of the different industry segments are not mutually exclusive. RENDERERS These firms are the first to handle and process (i.e., render) animal proteins and to send these processed materials to feed mills and/or protein blenders for use as a feed ingredient. Number of active firms whose initial inspection has been reported to FDA – 269 Number of active firms handling materials prohibited from use in ruminant feed – 161 (60 % of those active firms inspected) Of the 161 active firms handling prohibited materials, their most recent inspection revealed that: 0 firms (0.0 %) were classified as OAI 4 firms (2.5 %) were classified as VAI LICENSED FEED MILLS FDA licenses these feed mills to produce medicated feed products. The license is required to manufacture and distribute feed using certain potent drug products, usually those requiring some pre-slaughter withdrawal time. This licensing has nothing to do with handling prohibited materials under the feed ban regulation. A medicated feed license from FDA is not required to handle materials prohibited under the Ruminant Feed Ban. Number of active firms whose initial inspection has been reported to FDA – 1,074 Number of active firms handling materials prohibited from use in ruminant feed – 444 (41 % of those active firms inspected) Of the 444 active firms handling prohibited materials, their most recent inspection revealed that: 0 firms (0.0 %) were classified as OAI 5 firms (1.1 %) were classified as VAI FEED MILLS NOT LICENSED BY FDA These feed mills are not licensed by the FDA to produce medicated feeds. Number of active firms whose initial inspection has been reported to FDA – 5,183 Number of active firms handling materials prohibited from use in ruminant feed – 2,391 (46 % of those active firms inspected) Of the 2,391 active firms handling prohibited materials, their most recent inspection revealed that: 3 firms (0.1 %) were classified as OAI 56 firms (2.3 %) were classified as VAI PROTEIN BLENDERS These firms blend rendered animal protein for the purpose of producing quality feed ingredients that will be used by feed mills. Number of active firms whose initial inspection has been reported to FDA – 386 Number of active firms handling materials prohibited from use in ruminant feed – 183 (47% of those active firms inspected) Of the 183 active firms handling prohibited materials, their most recent inspection revealed that: 1 firm (0.5 %) was classified as OAI 7 firms (3.8 %) were classified as VAI RENDERERS, FEED MILLS, AND PROTEIN BLENDERS MANUFACTURING WITH PROHIBITED MATERIAL This category includes only those firms that actually use prohibited material to manufacture, process, or blend animal feed or feed ingredients. Total number of active renderers, feed mills, and protein blenders whose initial inspection has been reported to FDA – 6,604 Number of active renderers, feed mills, and protein blenders processing with prohibited materials – 497 (7.5 %) Of the 497 active renderers, feed mills, and protein blenders processing with prohibited materials, their most recent inspection revealed that: 2 firms (0.4 %) were classified as OAI 24 firms (4.8 %) were classified as VAI OTHER FIRMS INSPECTED Examples of such firms include ruminant feeders, on-farm mixers, pet food manufacturers, animal feed salvagers, distributors, retailers, and animal feed transporters. Number of active firms whose initial inspection has been reported to FDA – 17,227 Number of active firms handling materials prohibited from use in ruminant feed – 5,415 (31% of those active firms inspected) Of the 5,415 active firms handling prohibited materials, their most recent inspection revealed that: 2 firms (0.04 %) were classified as OAI 186 firms (3.4%) were classified as VAI TOTAL FIRMS Note that a single firm can be reported under more than one firm category; therefore, the summation of the individual OAI/VAI firm categories will be more than the actual total number of OAI/VAI firms, as presented below. Number of active firms whose initial inspection has been reported to FDA – 19,705 Number of active firms handling materials prohibited from use in ruminant feed – 6,146 (31 % of those active firms inspected) Of the 6,146 active firms handling prohibited materials, their most recent inspection revealed that: 3 firms (0.05 %) were classified as OAI 200 firms (3.3 %) were classified as VAI ---------------------------------------------------------------------------- ---- Issued by: FDA, Center for Veterinary Medicine, Communications Staff, HFV-12 7519 Standish Place, Rockville, MD 20855 Telephone: (240) 276-9300 FAX: (240) 276-9115 Internet Web Site: [url=http://www.fda.gov/cvm]http://www.fda.gov/cvm[/url] [url=http://www.fda.gov/cvm/CVM_Updates/BSE0507.htm]http://www.fda.gov/cvm/CVM_Updates/BSE0507.htm[/url] 10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA 2007 Date: March 21, 2007 at 2:27 pm PST RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II ___________________________________ PRODUCT Bulk cattle feed made with recalled Darling’s 85% Blood Meal, Flash Dried, Recall # V-024-2007 CODE Cattle feed delivered between 01/12/2007 and 01/26/2007 RECALLING FIRM/MANUFACTURER Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007. Firm initiated recall is ongoing. REASON Blood meal used to make cattle feed was recalled because it was cross-contaminated with prohibited bovine meat and bone meal that had been manufactured on common equipment and labeling did not bear cautionary BSE statement. VOLUME OF PRODUCT IN COMMERCE 42,090 lbs. DISTRIBUTION WI ___________________________________ PRODUCT Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL Prot-Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal, TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI – 8# SPECIAL DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J – PROTEIN/LACTATION, ROCK CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY, A-BYPASS ML W/SMARTA, Recall # V-025-2007 CODE The firm does not utilize a code - only shipping documentation with commodity and weights identified. RECALLING FIRM/MANUFACTURER Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm initiated recall is complete. REASON Products manufactured from bulk feed containing blood meal that was cross contaminated with prohibited meat and bone meal and the labeling did not bear cautionary BSE statement. VOLUME OF PRODUCT IN COMMERCE 9,997,976 lbs. DISTRIBUTION ID and NV END OF ENFORCEMENT REPORT FOR MARCH 21, 2007 [url=http://www.fda.gov/bbs/topics/enforce/2007/ENF00996.html]http://www.fda.gov/bbs/topics/enforce/2 ... 00996.html[/url] > May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE what about BASE ??? USA MAD COW STRAIN MORE VIRULENT TO HUMANS THAN UK STRAIN 18 January 2007 - Draft minutes of the SEAC 95 meeting (426 KB) held on 7 December 2006 are now available. snip... 64. A member noted that at the recent Neuroprion meeting, a study was presented showing that in transgenic mice BSE passaged in sheep may be more virulent and infectious to a wider range of species than bovine derived BSE. Other work presented suggested that BSE and bovine amyloidotic spongiform encephalopathy (BASE) MAY BE RELATED. A mutation had been identified in the prion protein gene in an AMERICAN BASE CASE THAT WAS SIMILAR IN NATURE TO A MUTATION FOUND IN CASES OF SPORADIC CJD. snip... [url=http://www.seac.gov.uk/minutes/95.pdf]http://www.seac.gov.uk/minutes/95.pdf[/url] 3:30 Transmission of the Italian Atypical BSE (BASE) in Humanized Mouse Models Qingzhong Kong, Ph.D., Assistant Professor, Pathology, Case Western Reserve University Bovine Amyloid Spongiform Encephalopathy (BASE) is an atypical BSE strain discovered recently in Italy, and similar or different atypical BSE cases were also reported in other countries. The infectivity and phenotypes of these atypical BSE strains in humans are unknown. In collaboration with Pierluigi Gambetti, as well as Maria Caramelli and her co-workers, we have inoculated transgenic mice expressing human prion protein with brain homogenates from BASE or BSE infected cattle. Our data shows that about half of the BASE-inoculated mice became infected with an average incubation time of about 19 months; in contrast, none of the BSE-inoculated mice appear to be infected after more than 2 years. ***These results indicate that BASE is transmissible to humans and suggest that BASE is more virulent than classical BSE in humans.*** 6:30 Close of Day One [url=http://www.healthtech.com/2007/tse/day1.asp]http://www.healthtech.com/2007/tse/day1.asp[/url] SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM 1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype of 'UNKNOWN' strain growing. ... [url=http://www.cjdsurveillance.com/resources-casereport.html]http://www.cjdsurveillance.com/resource ... eport.html[/url] There is a growing number of human CJD cases, and they were presented last week in San Francisco by Luigi Gambatti(?) from his CJD surveillance collection. He estimates that it may be up to 14 or 15 persons which display selectively SPRPSC and practically no detected RPRPSC proteins. [url=http://www.fda.gov/ohrms/dockets/ac/06/transcripts/1006-4240t1.htm]http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.htm[/url] [url=http://www.fda.gov/ohrms/dockets/ac/06/transcripts/2006-4240t1.pdf]http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.pdf[/url] TSS [/QUOTE]
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