Subject: May 2007 Update on Feed Enforcement Activities to Limit the Spread
of BSE
Date: May 21, 2007 at 1:59 pm PST
greetings,
WOW, some feed ban. you would have thought by now the infamous August 4,
1997 mad cow feed ban would have taken place by now. from the mad cow feed
ban warning letter just several months ago, where 10,000,000 LBS of banned
material went out into commerce to be fed out again, I cannot imagine how
much more tainted product is out there from the looks of this latest report.
...terry
CVM Update
May 18, 2007
May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE
To help prevent the establishment and amplification of Bovine Spongiform
Encephalopathy (BSE) through feed in the United States, the Food and Drug
Administration (FDA) implemented a final rule that prohibits the use of most
mammalian protein in feeds for ruminant animals. This rule, Title 21 Part
589.2000 of the Code of Federal Regulations, here called the Ruminant Feed
Ban, became effective on August 4, 1997.
The following is an update on FDA enforcement activities regarding the
ruminant feed ban. FDA's Center for Veterinary Medicine (CVM) has assembled
data from the inspections that have been conducted AND whose final
inspection report has been recorded in the FDA's inspection database as of
May 12, 2007. As of May 12, 2007, FDA had received over 53,000 inspection
reports. The majority of these inspections (around 68%) were conducted by
State feed safety officials, with the remainder conducted by FDA officials.
Inspections conducted by FDA or State investigators are classified to
reflect the compliance status at the time of the inspection based upon the
objectionable conditions documented. These inspection conclusions are
reported as Official Action Indicated (OAI), Voluntary Action Indicated
(VAI), or No Action Indicated (NAI).
An OAI inspection classification occurs when significant objectionable
conditions or practices were found and regulatory sanctions are warranted in
order to address the establishment's lack of compliance with the regulation.
An example of an OAI inspection classification would be findings of
manufacturing procedures insufficient to ensure that ruminant feed is not
contaminated with prohibited material. Inspections classified with OAI
violations will be promptly re-inspected following the regulatory sanctions
to determine whether adequate corrective actions have been implemented.
A VAI inspection classification occurs when objectionable conditions or
practices were found that do not meet the threshold of regulatory
significance, but do warrant advisory actions to inform the establishment of
findings that should be voluntarily corrected. Inspections classified with
VAI violations are more technical violations of the Ruminant Feed Ban. These
include provisions such as minor recordkeeping lapses and conditions
involving non-ruminant feeds.
An NAI inspection classification occurs when no objectionable conditions or
practices were found during the inspection or the significance of the
documented objectionable conditions found does not justify further actions.
The results to date are reported here both by "segment of industry" and "in
total". NOTE – A single firm can operate as more than one firm type. As a
result, the categories of the different industry segments are not mutually
exclusive.
RENDERERS
These firms are the first to handle and process (i.e., render) animal
proteins and to send these processed materials to feed mills and/or protein
blenders for use as a feed ingredient.
Number of active firms whose initial inspection has been reported to FDA –
269
Number of active firms handling materials prohibited from use in ruminant
feed – 161 (60 % of those active firms inspected)
Of the 161 active firms handling prohibited materials, their most recent
inspection revealed that:
0 firms (0.0 %) were classified as OAI
4 firms (2.5 %) were classified as VAI
LICENSED FEED MILLS
FDA licenses these feed mills to produce medicated feed products. The
license is required to manufacture and distribute feed using certain potent
drug products, usually those requiring some pre-slaughter withdrawal time.
This licensing has nothing to do with handling prohibited materials under
the feed ban regulation. A medicated feed license from FDA is not required
to handle materials prohibited under the Ruminant Feed Ban.
Number of active firms whose initial inspection has been reported to FDA –
1,074
Number of active firms handling materials prohibited from use in ruminant
feed – 444 (41 % of those active firms inspected)
Of the 444 active firms handling prohibited materials, their most recent
inspection revealed that:
0 firms (0.0 %) were classified as OAI
5 firms (1.1 %) were classified as VAI
FEED MILLS NOT LICENSED BY FDA
These feed mills are not licensed by the FDA to produce medicated feeds.
Number of active firms whose initial inspection has been reported to FDA –
5,183
Number of active firms handling materials prohibited from use in ruminant
feed – 2,391 (46 % of those active firms inspected)
Of the 2,391 active firms handling prohibited materials, their most recent
inspection revealed that:
3 firms (0.1 %) were classified as OAI
56 firms (2.3 %) were classified as VAI
PROTEIN BLENDERS
These firms blend rendered animal protein for the purpose of producing
quality feed ingredients that will be used by feed mills.
Number of active firms whose initial inspection has been reported to FDA –
386
Number of active firms handling materials prohibited from use in ruminant
feed – 183 (47% of those active firms inspected)
Of the 183 active firms handling prohibited materials, their most recent
inspection revealed that:
1 firm (0.5 %) was classified as OAI
7 firms (3.8 %) were classified as VAI
RENDERERS, FEED MILLS, AND PROTEIN BLENDERS MANUFACTURING WITH PROHIBITED
MATERIAL
This category includes only those firms that actually use prohibited
material to manufacture, process, or blend animal feed or feed ingredients.
Total number of active renderers, feed mills, and protein blenders whose
initial inspection has been reported to FDA – 6,604
Number of active renderers, feed mills, and protein blenders processing with
prohibited materials – 497 (7.5 %)
Of the 497 active renderers, feed mills, and protein blenders processing
with prohibited materials, their most recent inspection revealed that:
2 firms (0.4 %) were classified as OAI
24 firms (4.8 %) were classified as VAI
OTHER FIRMS INSPECTED
Examples of such firms include ruminant feeders, on-farm mixers, pet food
manufacturers, animal feed salvagers, distributors, retailers, and animal
feed transporters.
Number of active firms whose initial inspection has been reported to FDA –
17,227
Number of active firms handling materials prohibited from use in ruminant
feed – 5,415 (31% of those active firms inspected)
Of the 5,415 active firms handling prohibited materials, their most recent
inspection revealed that:
2 firms (0.04 %) were classified as OAI
186 firms (3.4%) were classified as VAI
TOTAL FIRMS
Note that a single firm can be reported under more than one firm category;
therefore, the summation of the individual OAI/VAI firm categories will be
more than the actual total number of OAI/VAI firms, as presented below.
Number of active firms whose initial inspection has been reported to FDA –
19,705
Number of active firms handling materials prohibited from use in ruminant
feed – 6,146 (31 % of those active firms inspected)
Of the 6,146 active firms handling prohibited materials, their most recent
inspection revealed that:
3 firms (0.05 %) were classified as OAI
200 firms (3.3 %) were classified as VAI
----------------------------------------------------------------------------
----
Issued by:
FDA, Center for Veterinary Medicine,
Communications Staff, HFV-12
7519 Standish Place, Rockville, MD 20855
Telephone: (240) 276-9300 FAX: (240) 276-9115
Internet Web Site: http://www.fda.gov/cvm
http://www.fda.gov/cvm/CVM_Updates/BSE0507.htm
10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA
2007
Date: March 21, 2007 at 2:27 pm PST
RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II
___________________________________
PRODUCT
Bulk cattle feed made with recalled Darling's 85% Blood Meal, Flash Dried,
Recall # V-024-2007
CODE
Cattle feed delivered between 01/12/2007 and 01/26/2007
RECALLING FIRM/MANUFACTURER
Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007.
Firm initiated recall is ongoing.
REASON
Blood meal used to make cattle feed was recalled because it was
cross-contaminated with prohibited bovine meat and bone meal that had been
manufactured on common equipment and labeling did not bear cautionary BSE
statement.
VOLUME OF PRODUCT IN COMMERCE
42,090 lbs.
DISTRIBUTION
WI
___________________________________
PRODUCT
Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL
Prot-Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal,
TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY
Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST
POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI – 8# SPECIAL
DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J – PROTEIN/LACTATION, ROCK
CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC
MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY,
A-BYPASS ML W/SMARTA, Recall # V-025-2007
CODE
The firm does not utilize a code - only shipping documentation with
commodity and weights identified.
RECALLING FIRM/MANUFACTURER
Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm
initiated recall is complete.
REASON
Products manufactured from bulk feed containing blood meal that was cross
contaminated with prohibited meat and bone meal and the labeling did not
bear cautionary BSE statement.
VOLUME OF PRODUCT IN COMMERCE
9,997,976 lbs.
DISTRIBUTION
ID and NV
END OF ENFORCEMENT REPORT FOR MARCH 21, 2007
http://www.fda.gov/bbs/topics/enforce/2 ... 00996.html
> May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE
what about BASE ???
USA MAD COW STRAIN MORE VIRULENT TO HUMANS THAN UK STRAIN
18 January 2007 - Draft minutes of the SEAC 95 meeting (426 KB) held on 7
December 2006 are now available.
snip...
64. A member noted that at the recent Neuroprion meeting, a study was
presented showing that in transgenic mice BSE passaged in sheep may be more
virulent and infectious to a wider range of species than bovine derived BSE.
Other work presented suggested that BSE and bovine amyloidotic spongiform
encephalopathy (BASE) MAY BE RELATED. A mutation had been identified in the
prion protein gene in an AMERICAN BASE CASE THAT WAS SIMILAR IN NATURE TO A
MUTATION FOUND IN CASES OF SPORADIC CJD.
snip...
http://www.seac.gov.uk/minutes/95.pdf
3:30 Transmission of the Italian Atypical BSE (BASE) in Humanized Mouse
Models Qingzhong Kong, Ph.D., Assistant Professor, Pathology, Case Western
Reserve
University
Bovine Amyloid Spongiform Encephalopathy (BASE) is an atypical BSE strain
discovered recently in Italy, and similar or different atypical BSE cases
were also reported in other countries. The infectivity and phenotypes of
these atypical BSE strains in humans are unknown. In collaboration with
Pierluigi Gambetti, as well as Maria Caramelli and her co-workers, we have
inoculated transgenic mice expressing human prion protein with brain
homogenates from BASE or BSE infected cattle. Our data shows that about half
of the BASE-inoculated mice became infected with an average incubation time
of about 19 months; in contrast, none of the BSE-inoculated mice appear to
be infected after more than 2 years.
***These results indicate that BASE is transmissible to humans and suggest
that BASE is more virulent than
classical BSE in humans.***
6:30 Close of Day One
http://www.healthtech.com/2007/tse/day1.asp
SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM
1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype
of 'UNKNOWN' strain growing. ...
http://www.cjdsurveillance.com/resource ... eport.html
There is a growing number of human CJD cases, and they were presented last
week in San Francisco by Luigi Gambatti(?) from his CJD surveillance
collection.
He estimates that it may be up to 14 or 15 persons which display selectively
SPRPSC and practically no detected RPRPSC proteins.
http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.htm
http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.pdf
TSS
of BSE
Date: May 21, 2007 at 1:59 pm PST
greetings,
WOW, some feed ban. you would have thought by now the infamous August 4,
1997 mad cow feed ban would have taken place by now. from the mad cow feed
ban warning letter just several months ago, where 10,000,000 LBS of banned
material went out into commerce to be fed out again, I cannot imagine how
much more tainted product is out there from the looks of this latest report.
...terry
CVM Update
May 18, 2007
May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE
To help prevent the establishment and amplification of Bovine Spongiform
Encephalopathy (BSE) through feed in the United States, the Food and Drug
Administration (FDA) implemented a final rule that prohibits the use of most
mammalian protein in feeds for ruminant animals. This rule, Title 21 Part
589.2000 of the Code of Federal Regulations, here called the Ruminant Feed
Ban, became effective on August 4, 1997.
The following is an update on FDA enforcement activities regarding the
ruminant feed ban. FDA's Center for Veterinary Medicine (CVM) has assembled
data from the inspections that have been conducted AND whose final
inspection report has been recorded in the FDA's inspection database as of
May 12, 2007. As of May 12, 2007, FDA had received over 53,000 inspection
reports. The majority of these inspections (around 68%) were conducted by
State feed safety officials, with the remainder conducted by FDA officials.
Inspections conducted by FDA or State investigators are classified to
reflect the compliance status at the time of the inspection based upon the
objectionable conditions documented. These inspection conclusions are
reported as Official Action Indicated (OAI), Voluntary Action Indicated
(VAI), or No Action Indicated (NAI).
An OAI inspection classification occurs when significant objectionable
conditions or practices were found and regulatory sanctions are warranted in
order to address the establishment's lack of compliance with the regulation.
An example of an OAI inspection classification would be findings of
manufacturing procedures insufficient to ensure that ruminant feed is not
contaminated with prohibited material. Inspections classified with OAI
violations will be promptly re-inspected following the regulatory sanctions
to determine whether adequate corrective actions have been implemented.
A VAI inspection classification occurs when objectionable conditions or
practices were found that do not meet the threshold of regulatory
significance, but do warrant advisory actions to inform the establishment of
findings that should be voluntarily corrected. Inspections classified with
VAI violations are more technical violations of the Ruminant Feed Ban. These
include provisions such as minor recordkeeping lapses and conditions
involving non-ruminant feeds.
An NAI inspection classification occurs when no objectionable conditions or
practices were found during the inspection or the significance of the
documented objectionable conditions found does not justify further actions.
The results to date are reported here both by "segment of industry" and "in
total". NOTE – A single firm can operate as more than one firm type. As a
result, the categories of the different industry segments are not mutually
exclusive.
RENDERERS
These firms are the first to handle and process (i.e., render) animal
proteins and to send these processed materials to feed mills and/or protein
blenders for use as a feed ingredient.
Number of active firms whose initial inspection has been reported to FDA –
269
Number of active firms handling materials prohibited from use in ruminant
feed – 161 (60 % of those active firms inspected)
Of the 161 active firms handling prohibited materials, their most recent
inspection revealed that:
0 firms (0.0 %) were classified as OAI
4 firms (2.5 %) were classified as VAI
LICENSED FEED MILLS
FDA licenses these feed mills to produce medicated feed products. The
license is required to manufacture and distribute feed using certain potent
drug products, usually those requiring some pre-slaughter withdrawal time.
This licensing has nothing to do with handling prohibited materials under
the feed ban regulation. A medicated feed license from FDA is not required
to handle materials prohibited under the Ruminant Feed Ban.
Number of active firms whose initial inspection has been reported to FDA –
1,074
Number of active firms handling materials prohibited from use in ruminant
feed – 444 (41 % of those active firms inspected)
Of the 444 active firms handling prohibited materials, their most recent
inspection revealed that:
0 firms (0.0 %) were classified as OAI
5 firms (1.1 %) were classified as VAI
FEED MILLS NOT LICENSED BY FDA
These feed mills are not licensed by the FDA to produce medicated feeds.
Number of active firms whose initial inspection has been reported to FDA –
5,183
Number of active firms handling materials prohibited from use in ruminant
feed – 2,391 (46 % of those active firms inspected)
Of the 2,391 active firms handling prohibited materials, their most recent
inspection revealed that:
3 firms (0.1 %) were classified as OAI
56 firms (2.3 %) were classified as VAI
PROTEIN BLENDERS
These firms blend rendered animal protein for the purpose of producing
quality feed ingredients that will be used by feed mills.
Number of active firms whose initial inspection has been reported to FDA –
386
Number of active firms handling materials prohibited from use in ruminant
feed – 183 (47% of those active firms inspected)
Of the 183 active firms handling prohibited materials, their most recent
inspection revealed that:
1 firm (0.5 %) was classified as OAI
7 firms (3.8 %) were classified as VAI
RENDERERS, FEED MILLS, AND PROTEIN BLENDERS MANUFACTURING WITH PROHIBITED
MATERIAL
This category includes only those firms that actually use prohibited
material to manufacture, process, or blend animal feed or feed ingredients.
Total number of active renderers, feed mills, and protein blenders whose
initial inspection has been reported to FDA – 6,604
Number of active renderers, feed mills, and protein blenders processing with
prohibited materials – 497 (7.5 %)
Of the 497 active renderers, feed mills, and protein blenders processing
with prohibited materials, their most recent inspection revealed that:
2 firms (0.4 %) were classified as OAI
24 firms (4.8 %) were classified as VAI
OTHER FIRMS INSPECTED
Examples of such firms include ruminant feeders, on-farm mixers, pet food
manufacturers, animal feed salvagers, distributors, retailers, and animal
feed transporters.
Number of active firms whose initial inspection has been reported to FDA –
17,227
Number of active firms handling materials prohibited from use in ruminant
feed – 5,415 (31% of those active firms inspected)
Of the 5,415 active firms handling prohibited materials, their most recent
inspection revealed that:
2 firms (0.04 %) were classified as OAI
186 firms (3.4%) were classified as VAI
TOTAL FIRMS
Note that a single firm can be reported under more than one firm category;
therefore, the summation of the individual OAI/VAI firm categories will be
more than the actual total number of OAI/VAI firms, as presented below.
Number of active firms whose initial inspection has been reported to FDA –
19,705
Number of active firms handling materials prohibited from use in ruminant
feed – 6,146 (31 % of those active firms inspected)
Of the 6,146 active firms handling prohibited materials, their most recent
inspection revealed that:
3 firms (0.05 %) were classified as OAI
200 firms (3.3 %) were classified as VAI
----------------------------------------------------------------------------
----
Issued by:
FDA, Center for Veterinary Medicine,
Communications Staff, HFV-12
7519 Standish Place, Rockville, MD 20855
Telephone: (240) 276-9300 FAX: (240) 276-9115
Internet Web Site: http://www.fda.gov/cvm
http://www.fda.gov/cvm/CVM_Updates/BSE0507.htm
10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA
2007
Date: March 21, 2007 at 2:27 pm PST
RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II
___________________________________
PRODUCT
Bulk cattle feed made with recalled Darling's 85% Blood Meal, Flash Dried,
Recall # V-024-2007
CODE
Cattle feed delivered between 01/12/2007 and 01/26/2007
RECALLING FIRM/MANUFACTURER
Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007.
Firm initiated recall is ongoing.
REASON
Blood meal used to make cattle feed was recalled because it was
cross-contaminated with prohibited bovine meat and bone meal that had been
manufactured on common equipment and labeling did not bear cautionary BSE
statement.
VOLUME OF PRODUCT IN COMMERCE
42,090 lbs.
DISTRIBUTION
WI
___________________________________
PRODUCT
Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL
Prot-Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal,
TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY
Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST
POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI – 8# SPECIAL
DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J – PROTEIN/LACTATION, ROCK
CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC
MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY,
A-BYPASS ML W/SMARTA, Recall # V-025-2007
CODE
The firm does not utilize a code - only shipping documentation with
commodity and weights identified.
RECALLING FIRM/MANUFACTURER
Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm
initiated recall is complete.
REASON
Products manufactured from bulk feed containing blood meal that was cross
contaminated with prohibited meat and bone meal and the labeling did not
bear cautionary BSE statement.
VOLUME OF PRODUCT IN COMMERCE
9,997,976 lbs.
DISTRIBUTION
ID and NV
END OF ENFORCEMENT REPORT FOR MARCH 21, 2007
http://www.fda.gov/bbs/topics/enforce/2 ... 00996.html
> May 2007 Update on Feed Enforcement Activities to Limit the Spread of BSE
what about BASE ???
USA MAD COW STRAIN MORE VIRULENT TO HUMANS THAN UK STRAIN
18 January 2007 - Draft minutes of the SEAC 95 meeting (426 KB) held on 7
December 2006 are now available.
snip...
64. A member noted that at the recent Neuroprion meeting, a study was
presented showing that in transgenic mice BSE passaged in sheep may be more
virulent and infectious to a wider range of species than bovine derived BSE.
Other work presented suggested that BSE and bovine amyloidotic spongiform
encephalopathy (BASE) MAY BE RELATED. A mutation had been identified in the
prion protein gene in an AMERICAN BASE CASE THAT WAS SIMILAR IN NATURE TO A
MUTATION FOUND IN CASES OF SPORADIC CJD.
snip...
http://www.seac.gov.uk/minutes/95.pdf
3:30 Transmission of the Italian Atypical BSE (BASE) in Humanized Mouse
Models Qingzhong Kong, Ph.D., Assistant Professor, Pathology, Case Western
Reserve
University
Bovine Amyloid Spongiform Encephalopathy (BASE) is an atypical BSE strain
discovered recently in Italy, and similar or different atypical BSE cases
were also reported in other countries. The infectivity and phenotypes of
these atypical BSE strains in humans are unknown. In collaboration with
Pierluigi Gambetti, as well as Maria Caramelli and her co-workers, we have
inoculated transgenic mice expressing human prion protein with brain
homogenates from BASE or BSE infected cattle. Our data shows that about half
of the BASE-inoculated mice became infected with an average incubation time
of about 19 months; in contrast, none of the BSE-inoculated mice appear to
be infected after more than 2 years.
***These results indicate that BASE is transmissible to humans and suggest
that BASE is more virulent than
classical BSE in humans.***
6:30 Close of Day One
http://www.healthtech.com/2007/tse/day1.asp
SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM
1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype
of 'UNKNOWN' strain growing. ...
http://www.cjdsurveillance.com/resource ... eport.html
There is a growing number of human CJD cases, and they were presented last
week in San Francisco by Luigi Gambatti(?) from his CJD surveillance
collection.
He estimates that it may be up to 14 or 15 persons which display selectively
SPRPSC and practically no detected RPRPSC proteins.
http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.htm
http://www.fda.gov/ohrms/dockets/ac/06/ ... 4240t1.pdf
TSS
