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Air under the skin?
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<blockquote data-quote="Barney" data-source="post: 773041" data-attributes="member: 14509"><p>I wasn't really thinking "food" animal. I guess I was looking at it from my point of view, which was just saving the animals life. Believe me, I am well aware of FDA rules and regulations on drugs. I have a Phd in Pharmaceutical Research and have spent every working day for the last 35 yrs dealing with their drug rules. I recently retired, so I don't have to deal with the BS anymore. I guess I have tunnel vision on saving lives and I really didn't think about the food consumption end, if the calf makes it. If I had one this sick and nursed it back to health, it would just be one of my "pets." No way I could ever eat it! Plus the calf is so sick now, my personal opinion, he shouldn't be consumed by anyone. Rocephin has been studies and used in cows, but I don't think anything has been submitted for Vancomycin. The pharmacokinetics and dosage regimen of Rocephin were investigated in buffalo calves following a single intravenous administration of Rocephin (10 mg/kg). The elimination rate constant was 0.18±0.01 h–1 and the elimination half-life was 3.79±0.09 h. The apparent volume of distribution was 1.40±0.01 L/kg and the total plasma clearance was 0.26±0.01 L/(kg h). Approximately 43% of total administered dose of Rocephin was excreted in urine within 8 h. To maintain a minimum therapeutic concentration of 1 g/ml, a satisfactory intravenous dosage regimen of Rocephin in buffalo calves iwas determined to be 13 mg/kg repeated at 12 h intervals. I do not recommend antibiotics unless there is an active infection. Antibiotics are overused in the food production industry, and overprescribed by physicians. </p><p></p><p>Barney</p></blockquote><p></p>
[QUOTE="Barney, post: 773041, member: 14509"] I wasn't really thinking "food" animal. I guess I was looking at it from my point of view, which was just saving the animals life. Believe me, I am well aware of FDA rules and regulations on drugs. I have a Phd in Pharmaceutical Research and have spent every working day for the last 35 yrs dealing with their drug rules. I recently retired, so I don't have to deal with the BS anymore. I guess I have tunnel vision on saving lives and I really didn't think about the food consumption end, if the calf makes it. If I had one this sick and nursed it back to health, it would just be one of my "pets." No way I could ever eat it! Plus the calf is so sick now, my personal opinion, he shouldn't be consumed by anyone. Rocephin has been studies and used in cows, but I don't think anything has been submitted for Vancomycin. The pharmacokinetics and dosage regimen of Rocephin were investigated in buffalo calves following a single intravenous administration of Rocephin (10 mg/kg). The elimination rate constant was 0.18±0.01 h–1 and the elimination half-life was 3.79±0.09 h. The apparent volume of distribution was 1.40±0.01 L/kg and the total plasma clearance was 0.26±0.01 L/(kg h). Approximately 43% of total administered dose of Rocephin was excreted in urine within 8 h. To maintain a minimum therapeutic concentration of 1 g/ml, a satisfactory intravenous dosage regimen of Rocephin in buffalo calves iwas determined to be 13 mg/kg repeated at 12 h intervals. I do not recommend antibiotics unless there is an active infection. Antibiotics are overused in the food production industry, and overprescribed by physicians. Barney [/QUOTE]
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