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NCBA, R-CALF, COOL, USDA (No Politics!)
TEXAS CONFIRMED HUMAN BSE VCJD IN ADULT MALE
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<blockquote data-quote="flounder" data-source="post: 1160331" data-attributes="member: 3519"><p>*** We hypothesize that both BSE prions and CWD prions passaged through felines will seed human recPrP more efficiently than BSE or CWD from the original hosts, evidence that the new host will dampen the species barrier between humans and BSE or CWD. The new host effect is particularly relevant as we investigate potential means of trans-species transmission of prion disease. </p><p> </p><p>SNIP...SEE FULL TEXT ;</p><p> </p><p>Monday, June 23, 2014 </p><p> </p><p>*** PRION 2014 CONFERENCE CHRONIC WASTING DISEASE CWD </p><p> </p><p>*** PPo3-7: Prion Transmission from Cervids to Humans is Strain-dependent </p><p> </p><p>*** Here we report that a human prion strain that had adopted the cervid prion protein (PrP) sequence through passage in cervidized transgenic mice efficiently infected transgenic mice expressing human PrP, </p><p> </p><p>*** indicating that the species barrier from cervid to humans is prion strain-dependent and humans can be vulnerable to novel cervid prion strains. </p><p> </p><p>PPo2-27: </p><p> </p><p>Generation of a Novel form of Human PrPSc by Inter-species Transmission of Cervid Prions </p><p> </p><p>*** Our findings suggest that CWD prions have the capability to infect humans, and that this ability depends on CWD strain adaptation, implying that the risk for human health progressively increases with the spread of CWD among cervids. </p><p> </p><p>PPo2-7: </p><p> </p><p>Biochemical and Biophysical Characterization of Different CWD Isolates </p><p> </p><p>*** The data presented here substantiate and expand previous reports on the existence of different CWD strains. </p><p> </p><p> </p><p>Envt.07: </p><p> </p><p>Pathological Prion Protein (PrPTSE) in Skeletal Muscles of Farmed and Free Ranging White-Tailed Deer Infected with Chronic Wasting Disease </p><p> </p><p>***The presence and seeding activity of PrPTSE in skeletal muscle from CWD-infected cervids suggests prevention of such tissue in the human diet as a precautionary measure for food safety, pending on further clarification of whether CWD may be transmissible to humans. </p><p></p><p> >>>CHRONIC WASTING DISEASE , THERE WAS NO ABSOLUTE BARRIER TO CONVERSION OF THE HUMAN PRION PROTEIN<<< </p><p></p><p> *** PRICE OF CWD TSE PRION POKER GOES UP 2014 *** </p><p> </p><p>Transmissible Spongiform Encephalopathy TSE PRION update January 2, 2014 </p><p> </p><p>Wednesday, January 01, 2014 </p><p> </p><p>Molecular Barriers to Zoonotic Transmission of Prions </p><p> </p><p>*** chronic wasting disease, there was no absolute barrier to conversion of the human prion protein. </p><p> </p><p>*** Furthermore, the form of human PrPres produced in this in vitro assay when seeded with CWD, resembles that found in the most common human prion disease, namely sCJD of the MM1 subtype. </p><p> </p><p> </p><p>PRION2013 CONGRESSIONAL ABSTRACTS CWD </p><p> </p><p>Sunday, August 25, 2013 </p><p> </p><p>HD.13: CWD infection in the spleen of humanized transgenic mice </p><p> </p><p>***These results indicate that the CWD prion may have the potential to infect human peripheral lymphoid tissues. </p><p> </p><p>Oral.15: Molecular barriers to zoonotic prion transmission: Comparison of the ability of sheep, cattle and deer prion disease isolates to convert normal human prion protein to its pathological isoform in a cell-free system ***However, they also show that there is no absolute barrier ro conversion of human prion protein in the case of chronic wasting disease. </p><p> </p><p>there is in fact evidence that the potential for cwd transmission to humans can NOT be ruled out. </p><p> </p><p>I thought your readers and hunters and those that consume the venison, should have all the scientific facts, personally, I don't care what you eat, but if it effects me and my family down the road, it should then concern everyone, and the potential of iatrogenic transmission of the TSE prion is real i.e. 'friendly fire', medical, surgical, dental, blood, tissue, and or products there from...like deer antler velvet and TSE prions and nutritional supplements there from, all a potential risk factor that should not be ignored or silenced. ... </p><p> </p><p>the prion gods at the cdc state that there is ; </p><p> </p><p>''no strong evidence'' </p><p> </p><p>but let's see exactly what the authors of this cwd to human at the cdc state ; </p><p> </p><p>now, let's see what the authors said about this casual link, personal communications years ago. see where it is stated NO STRONG evidence. so, does this mean there IS casual evidence ???? </p><p> </p><p>"Our conclusion stating that we found no strong evidence of CWD transmission to humans" </p><p> </p><p>From: TSS (216-119-163-189.ipset45.wt.net) </p><p> </p><p>Subject: CWD aka MAD DEER/ELK TO HUMANS ??? </p><p> </p><p>Date: September 30, 2002 at 7:06 am PST </p><p> </p><p>From: "Belay, Ermias" </p><p> </p><p>To: </p><p> </p><p>Cc: "Race, Richard (NIH)" ; ; "Belay, Ermias" </p><p> </p><p>Sent: Monday, September 30, 2002 9:22 AM </p><p> </p><p>Subject: RE: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS </p><p> </p><p>Dear Sir/Madam, </p><p> </p><p>In the Archives of Neurology you quoted (the abstract of which was attached to your email), we did not say CWD in humans will present like variant CJD. </p><p> </p><p>That assumption would be wrong. I encourage you to read the whole article and call me if you have questions or need more clarification (phone: 404-639-3091). Also, we do not claim that "no-one has ever been infected with prion disease from eating venison." Our conclusion stating that we found no strong evidence of CWD transmission to humans in the article you quoted or in any other forum is limited to the patients we investigated. </p><p> </p><p>Ermias Belay, M.D. Centers for Disease Control and Prevention </p><p> </p><p>-----Original Message----- </p><p> </p><p>From: </p><p> </p><p>Sent: Sunday, September 29, 2002 10:15 AM </p><p> </p><p>To: rr26k @ nih.gov; rrace @ niaid.nih.gov; ebb8 @ CDC.GOV </p><p> </p><p>Subject: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS </p><p> </p><p>Sunday, November 10, 2002 6:26 PM ......snip........end..............TSS </p><p> </p><p>Thursday, April 03, 2008 </p><p> </p><p>A prion disease of cervids: Chronic wasting disease </p><p> </p><p>2008 1: Vet Res. 2008 Apr 3;39(4):41 </p><p> </p><p>A prion disease of cervids: Chronic wasting disease </p><p> </p><p>Sigurdson CJ. </p><p> </p><p>snip... </p><p> </p><p>*** twenty-seven CJD patients who regularly consumed venison were reported to the Surveillance Center***, </p><p> </p><p>snip... </p><p> </p><p> </p><p>***********CJD REPORT 1994 increased risk for consumption of veal and venison and lamb*********** </p><p> </p><p>CREUTZFELDT JAKOB DISEASE SURVEILLANCE IN THE UNITED KINGDOM THIRD ANNUAL REPORT AUGUST 1994 </p><p> </p><p>Consumption of venison and veal was much less widespread among both cases and controls. For both of these meats there was evidence of a trend with increasing frequency of consumption being associated with increasing risk of CJD. (not nvCJD, but sporadic CJD...tss) </p><p> </p><p>These associations were largely unchanged when attention was restricted to pairs with data obtained from relatives. ... </p><p> </p><p>Table 9 presents the results of an analysis of these data. </p><p> </p><p>There is STRONG evidence of an association between ''regular'' veal eating and risk of CJD (p = .0.01). </p><p> </p><p>Individuals reported to eat veal on average at least once a year appear to be at 13 TIMES THE RISK of individuals who have never eaten veal. </p><p> </p><p>There is, however, a very wide confidence interval around this estimate. There is no strong evidence that eating veal less than once per year is associated with increased risk of CJD (p = 0.51). </p><p> </p><p>The association between venison eating and risk of CJD shows similar pattern, with regular venison eating associated with a 9 FOLD INCREASE IN RISK OF CJD (p = 0.04). </p><p> </p><p>There is some evidence that risk of CJD INCREASES WITH INCREASING FREQUENCY OF LAMB EATING (p = 0.02). </p><p> </p><p>The evidence for such an association between beef eating and CJD is weaker (p = 0.14). When only controls for whom a relative was interviewed are included, this evidence becomes a little STRONGER (p = 0.08). </p><p> </p><p>snip... </p><p> </p><p>It was found that when veal was included in the model with another exposure, the association between veal and CJD remained statistically significant (p = < 0.05 for all exposures), while the other exposures ceased to be statistically significant (p = > 0.05). </p><p> </p><p>snip... </p><p> </p><p>In conclusion, an analysis of dietary histories revealed statistical associations between various meats/animal products and INCREASED RISK OF CJD. When some account was taken of possible confounding, the association between VEAL EATING AND RISK OF CJD EMERGED AS THE STRONGEST OF THESE ASSOCIATIONS STATISTICALLY. ... </p><p> </p><p>snip... </p><p> </p><p>In the study in the USA, a range of foodstuffs were associated with an increased risk of CJD, including liver consumption which was associated with an apparent SIX-FOLD INCREASE IN THE RISK OF CJD. By comparing the data from 3 studies in relation to this particular dietary factor, the risk of liver consumption became non-significant with an odds ratio of 1.2 (PERSONAL COMMUNICATION, PROFESSOR A. HOFMAN. ERASMUS UNIVERSITY, ROTTERDAM). (???...TSS) </p><p> </p><p>snip...see full report ; </p><p> </p><p><a href="http://collections.europarchive.org/tna/20090505194948/http://bseinquiry.gov.uk/files/yb/1994/08/00004001.pdf" target="_blank">http://collections.europarchive.org/tna ... 004001.pdf</a> </p><p> </p><p>Thursday, October 10, 2013 </p><p> </p><p>*************CJD REPORT 1994 increased risk for consumption of veal and venison and lamb************** </p><p> </p><p>CJD9/10022 </p><p> </p><p>October 1994 </p><p> </p><p>Mr R.N. Elmhirst Chairman British Deer Farmers Association Holly Lodge Spencers Lane BerksWell Coventry CV7 7BZ </p><p> </p><p>Dear Mr Elmhirst, </p><p> </p><p>CREUTZFELDT-JAKOB DISEASE (CJD) SURVEILLANCE UNIT REPORT </p><p> </p><p>Thank you for your recent letter concerning the publication of the third annual report from the CJD Surveillance Unit. I am sorry that you are dissatisfied with the way in which this report was published. </p><p> </p><p>The Surveillance Unit is a completely independant outside body and the Department of Health is committed to publishing their reports as soon as they become available. In the circumstances it is not the practice to circulate the report for comment since the findings of the report would not be amended. In future we can ensure that the British Deer Farmers Association receives a copy of the report in advance of publication. </p><p> </p><p>The Chief Medical Officer has undertaken to keep the public fully informed of the results of any research in respect of CJD. This report was entirely the work of the unit and was produced completely independantly of the the Department. </p><p> </p><p>The statistical results reqarding the consumption of venison was put into perspective in the body of the report and was not mentioned at all in the press release. Media attention regarding this report was low key but gave a realistic presentation of the statistical findings of the Unit. This approach to publication was successful in that consumption of venison was highlighted only once by the media ie. in the News at one television proqramme. </p><p> </p><p>I believe that a further statement about the report, or indeed statistical links between CJD and consumption of venison, would increase, and quite possibly give damaging credence, to the whole issue. From the low key media reports of which I am aware it seems unlikely that venison consumption will suffer adversely, if at all. </p><p> </p><p><a href="http://web.archive.org/web/20030511010117/http://www.bseinquiry.gov.uk/files/yb/1994/10/00003001.pdf" target="_blank">http://web.archive.org/web/200305110101 ... 003001.pdf</a> </p><p> </p><p>*** The potential impact of prion diseases on human health was greatly magnified by the recognition that interspecies transfer of BSE to humans by beef ingestion resulted in vCJD. While changes in animal feed constituents and slaughter practices appear to have curtailed vCJD, there is concern that CWD of free-ranging deer and elk in the U.S. might also cross the species barrier. Thus, consuming venison could be a source of human prion disease. Whether BSE and CWD represent interspecies scrapie transfer or are newly arisen prion diseases is unknown. Therefore, the possibility of transmission of prion disease through other food animals cannot be ruled out. There is evidence that vCJD can be transmitted through blood transfusion. There is likely a pool of unknown size of asymptomatic individuals infected with vCJD, and there may be asymptomatic individuals infected with the CWD equivalent. ***These circumstances represent a potential threat to blood, blood products, and plasma supplies. </p><p> </p><p><a href="http://cdmrp.army.mil/prevfunded/nprp/NPRP_Summit_Final_Report.pdf" target="_blank">http://cdmrp.army.mil/prevfunded/nprp/N ... Report.pdf</a> </p><p> </p><p>*** our results raise the possibility that CJD cases classified as VV1 may include cases caused by iatrogenic transmission of sCJD-MM1 prions or food-borne infection by type 1 prions from animals, e.g., chronic wasting disease prions in cervid. In fact, two CJD-VV1 patients who hunted deer or consumed venison have been reported (40, 41). The results of the present study emphasize the need for traceback studies and careful re-examination of the biochemical properties of sCJD-VV1 prions. *** </p><p> </p><p>Thursday, January 2, 2014 </p><p> </p><p>*** CWD TSE Prion in cervids to hTGmice, Heidenhain Variant Creutzfeldt-Jacob Disease MM1 genotype, and iatrogenic CJD ??? *** </p><p> </p><p><a href="http://transmissiblespongiformencephalopathy.blogspot.com/2014/01/cwd-tse-prion-in-cervids-to-htgmice.html" target="_blank">http://transmissiblespongiformencephalo ... gmice.html</a> </p><p> </p><p></p><p>just saying...kind regards, terry</p></blockquote><p></p>
[QUOTE="flounder, post: 1160331, member: 3519"] *** We hypothesize that both BSE prions and CWD prions passaged through felines will seed human recPrP more efficiently than BSE or CWD from the original hosts, evidence that the new host will dampen the species barrier between humans and BSE or CWD. The new host effect is particularly relevant as we investigate potential means of trans-species transmission of prion disease. SNIP...SEE FULL TEXT ; Monday, June 23, 2014 *** PRION 2014 CONFERENCE CHRONIC WASTING DISEASE CWD *** PPo3-7: Prion Transmission from Cervids to Humans is Strain-dependent *** Here we report that a human prion strain that had adopted the cervid prion protein (PrP) sequence through passage in cervidized transgenic mice efficiently infected transgenic mice expressing human PrP, *** indicating that the species barrier from cervid to humans is prion strain-dependent and humans can be vulnerable to novel cervid prion strains. PPo2-27: Generation of a Novel form of Human PrPSc by Inter-species Transmission of Cervid Prions *** Our findings suggest that CWD prions have the capability to infect humans, and that this ability depends on CWD strain adaptation, implying that the risk for human health progressively increases with the spread of CWD among cervids. PPo2-7: Biochemical and Biophysical Characterization of Different CWD Isolates *** The data presented here substantiate and expand previous reports on the existence of different CWD strains. Envt.07: Pathological Prion Protein (PrPTSE) in Skeletal Muscles of Farmed and Free Ranging White-Tailed Deer Infected with Chronic Wasting Disease ***The presence and seeding activity of PrPTSE in skeletal muscle from CWD-infected cervids suggests prevention of such tissue in the human diet as a precautionary measure for food safety, pending on further clarification of whether CWD may be transmissible to humans. >>>CHRONIC WASTING DISEASE , THERE WAS NO ABSOLUTE BARRIER TO CONVERSION OF THE HUMAN PRION PROTEIN<<< *** PRICE OF CWD TSE PRION POKER GOES UP 2014 *** Transmissible Spongiform Encephalopathy TSE PRION update January 2, 2014 Wednesday, January 01, 2014 Molecular Barriers to Zoonotic Transmission of Prions *** chronic wasting disease, there was no absolute barrier to conversion of the human prion protein. *** Furthermore, the form of human PrPres produced in this in vitro assay when seeded with CWD, resembles that found in the most common human prion disease, namely sCJD of the MM1 subtype. PRION2013 CONGRESSIONAL ABSTRACTS CWD Sunday, August 25, 2013 HD.13: CWD infection in the spleen of humanized transgenic mice ***These results indicate that the CWD prion may have the potential to infect human peripheral lymphoid tissues. Oral.15: Molecular barriers to zoonotic prion transmission: Comparison of the ability of sheep, cattle and deer prion disease isolates to convert normal human prion protein to its pathological isoform in a cell-free system ***However, they also show that there is no absolute barrier ro conversion of human prion protein in the case of chronic wasting disease. there is in fact evidence that the potential for cwd transmission to humans can NOT be ruled out. I thought your readers and hunters and those that consume the venison, should have all the scientific facts, personally, I don’t care what you eat, but if it effects me and my family down the road, it should then concern everyone, and the potential of iatrogenic transmission of the TSE prion is real i.e. ‘friendly fire’, medical, surgical, dental, blood, tissue, and or products there from...like deer antler velvet and TSE prions and nutritional supplements there from, all a potential risk factor that should not be ignored or silenced. ... the prion gods at the cdc state that there is ; ''no strong evidence'' but let's see exactly what the authors of this cwd to human at the cdc state ; now, let’s see what the authors said about this casual link, personal communications years ago. see where it is stated NO STRONG evidence. so, does this mean there IS casual evidence ???? “Our conclusion stating that we found no strong evidence of CWD transmission to humans” From: TSS (216-119-163-189.ipset45.wt.net) Subject: CWD aka MAD DEER/ELK TO HUMANS ??? Date: September 30, 2002 at 7:06 am PST From: "Belay, Ermias" To: Cc: "Race, Richard (NIH)" ; ; "Belay, Ermias" Sent: Monday, September 30, 2002 9:22 AM Subject: RE: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS Dear Sir/Madam, In the Archives of Neurology you quoted (the abstract of which was attached to your email), we did not say CWD in humans will present like variant CJD. That assumption would be wrong. I encourage you to read the whole article and call me if you have questions or need more clarification (phone: 404-639-3091). Also, we do not claim that "no-one has ever been infected with prion disease from eating venison." Our conclusion stating that we found no strong evidence of CWD transmission to humans in the article you quoted or in any other forum is limited to the patients we investigated. Ermias Belay, M.D. Centers for Disease Control and Prevention -----Original Message----- From: Sent: Sunday, September 29, 2002 10:15 AM To: rr26k @ nih.gov; rrace @ niaid.nih.gov; ebb8 @ CDC.GOV Subject: TO CDC AND NIH - PUB MED- 3 MORE DEATHS - CWD - YOUNG HUNTERS Sunday, November 10, 2002 6:26 PM ......snip........end..............TSS Thursday, April 03, 2008 A prion disease of cervids: Chronic wasting disease 2008 1: Vet Res. 2008 Apr 3;39(4):41 A prion disease of cervids: Chronic wasting disease Sigurdson CJ. snip... *** twenty-seven CJD patients who regularly consumed venison were reported to the Surveillance Center***, snip... ***********CJD REPORT 1994 increased risk for consumption of veal and venison and lamb*********** CREUTZFELDT JAKOB DISEASE SURVEILLANCE IN THE UNITED KINGDOM THIRD ANNUAL REPORT AUGUST 1994 Consumption of venison and veal was much less widespread among both cases and controls. For both of these meats there was evidence of a trend with increasing frequency of consumption being associated with increasing risk of CJD. (not nvCJD, but sporadic CJD...tss) These associations were largely unchanged when attention was restricted to pairs with data obtained from relatives. ... Table 9 presents the results of an analysis of these data. There is STRONG evidence of an association between ‘’regular’’ veal eating and risk of CJD (p = .0.01). Individuals reported to eat veal on average at least once a year appear to be at 13 TIMES THE RISK of individuals who have never eaten veal. There is, however, a very wide confidence interval around this estimate. There is no strong evidence that eating veal less than once per year is associated with increased risk of CJD (p = 0.51). The association between venison eating and risk of CJD shows similar pattern, with regular venison eating associated with a 9 FOLD INCREASE IN RISK OF CJD (p = 0.04). There is some evidence that risk of CJD INCREASES WITH INCREASING FREQUENCY OF LAMB EATING (p = 0.02). The evidence for such an association between beef eating and CJD is weaker (p = 0.14). When only controls for whom a relative was interviewed are included, this evidence becomes a little STRONGER (p = 0.08). snip... It was found that when veal was included in the model with another exposure, the association between veal and CJD remained statistically significant (p = < 0.05 for all exposures), while the other exposures ceased to be statistically significant (p = > 0.05). snip... In conclusion, an analysis of dietary histories revealed statistical associations between various meats/animal products and INCREASED RISK OF CJD. When some account was taken of possible confounding, the association between VEAL EATING AND RISK OF CJD EMERGED AS THE STRONGEST OF THESE ASSOCIATIONS STATISTICALLY. ... snip... In the study in the USA, a range of foodstuffs were associated with an increased risk of CJD, including liver consumption which was associated with an apparent SIX-FOLD INCREASE IN THE RISK OF CJD. By comparing the data from 3 studies in relation to this particular dietary factor, the risk of liver consumption became non-significant with an odds ratio of 1.2 (PERSONAL COMMUNICATION, PROFESSOR A. HOFMAN. ERASMUS UNIVERSITY, ROTTERDAM). (???...TSS) snip...see full report ; [url=http://collections.europarchive.org/tna/20090505194948/http://bseinquiry.gov.uk/files/yb/1994/08/00004001.pdf]http://collections.europarchive.org/tna ... 004001.pdf[/url] Thursday, October 10, 2013 *************CJD REPORT 1994 increased risk for consumption of veal and venison and lamb************** CJD9/10022 October 1994 Mr R.N. Elmhirst Chairman British Deer Farmers Association Holly Lodge Spencers Lane BerksWell Coventry CV7 7BZ Dear Mr Elmhirst, CREUTZFELDT-JAKOB DISEASE (CJD) SURVEILLANCE UNIT REPORT Thank you for your recent letter concerning the publication of the third annual report from the CJD Surveillance Unit. I am sorry that you are dissatisfied with the way in which this report was published. The Surveillance Unit is a completely independant outside body and the Department of Health is committed to publishing their reports as soon as they become available. In the circumstances it is not the practice to circulate the report for comment since the findings of the report would not be amended. In future we can ensure that the British Deer Farmers Association receives a copy of the report in advance of publication. The Chief Medical Officer has undertaken to keep the public fully informed of the results of any research in respect of CJD. This report was entirely the work of the unit and was produced completely independantly of the the Department. The statistical results reqarding the consumption of venison was put into perspective in the body of the report and was not mentioned at all in the press release. Media attention regarding this report was low key but gave a realistic presentation of the statistical findings of the Unit. This approach to publication was successful in that consumption of venison was highlighted only once by the media ie. in the News at one television proqramme. I believe that a further statement about the report, or indeed statistical links between CJD and consumption of venison, would increase, and quite possibly give damaging credence, to the whole issue. From the low key media reports of which I am aware it seems unlikely that venison consumption will suffer adversely, if at all. [url=http://web.archive.org/web/20030511010117/http://www.bseinquiry.gov.uk/files/yb/1994/10/00003001.pdf]http://web.archive.org/web/200305110101 ... 003001.pdf[/url] *** The potential impact of prion diseases on human health was greatly magnified by the recognition that interspecies transfer of BSE to humans by beef ingestion resulted in vCJD. While changes in animal feed constituents and slaughter practices appear to have curtailed vCJD, there is concern that CWD of free-ranging deer and elk in the U.S. might also cross the species barrier. Thus, consuming venison could be a source of human prion disease. Whether BSE and CWD represent interspecies scrapie transfer or are newly arisen prion diseases is unknown. Therefore, the possibility of transmission of prion disease through other food animals cannot be ruled out. There is evidence that vCJD can be transmitted through blood transfusion. There is likely a pool of unknown size of asymptomatic individuals infected with vCJD, and there may be asymptomatic individuals infected with the CWD equivalent. ***These circumstances represent a potential threat to blood, blood products, and plasma supplies. [url=http://cdmrp.army.mil/prevfunded/nprp/NPRP_Summit_Final_Report.pdf]http://cdmrp.army.mil/prevfunded/nprp/N ... Report.pdf[/url] *** our results raise the possibility that CJD cases classified as VV1 may include cases caused by iatrogenic transmission of sCJD-MM1 prions or food-borne infection by type 1 prions from animals, e.g., chronic wasting disease prions in cervid. In fact, two CJD-VV1 patients who hunted deer or consumed venison have been reported (40, 41). The results of the present study emphasize the need for traceback studies and careful re-examination of the biochemical properties of sCJD-VV1 prions. *** Thursday, January 2, 2014 *** CWD TSE Prion in cervids to hTGmice, Heidenhain Variant Creutzfeldt-Jacob Disease MM1 genotype, and iatrogenic CJD ??? *** [url=http://transmissiblespongiformencephalopathy.blogspot.com/2014/01/cwd-tse-prion-in-cervids-to-htgmice.html]http://transmissiblespongiformencephalo ... gmice.html[/url] just saying...kind regards, terry [/QUOTE]
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TEXAS CONFIRMED HUMAN BSE VCJD IN ADULT MALE
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