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NCBA, R-CALF, COOL, USDA (No Politics!)
TEXAS CONFIRMED HUMAN BSE VCJD IN ADULT MALE
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<blockquote data-quote="flounder" data-source="post: 1140605" data-attributes="member: 3519"><p><a href="http://madcowusda.blogspot.com/2012_06_01_archive.html" target="_blank">http://madcowusda.blogspot.com/2012_06_01_archive.html</a> </p><p> </p><p> </p><p>FDA MAD COW FEED BAN NOTHING BUT INK ON PAPER</p><p> </p><p>Note: On Dec. 23, 2003, the U.S. Department of Agriculture reported that a cow in Washington state had tested positive for bovine spongiform encephalopathy (BSE, or mad cow disease). As a result, information on this Web page stating that no BSE cases had been found in the United States is now incorrect. However, because other information on this page continues to have value, the page will remain available for viewing.</p><p> </p><p>FDA ANNOUNCES TEST RESULTS FROM TEXAS FEED LOT</p><p> </p><p>Today the Food and Drug Administration announced the results of tests taken on feed used at a Texas feedlot that was suspected of containing meat and bone meal from other domestic cattle -- a violation of FDA's 1997 prohibition on using ruminant material in feed for other ruminants. Results indicate that a very low level of prohibited material was found in the feed fed to cattle.</p><p> </p><p>FDA has determined that each animal could have consumed, at most and in total, five-and-one-half grams - approximately a quarter ounce -- of prohibited material. These animals weigh approximately 600 pounds.</p><p> </p><p>It is important to note that the prohibited material was domestic in origin (therefore not likely to contain infected material because there is no evidence of BSE in U.S. cattle), fed at a very low level, and fed only once. The potential risk of BSE to such cattle is therefore exceedingly low, even if the feed were contaminated.</p><p> </p><p>According to Dr. Bernard Schwetz, FDA's Acting Principal Deputy Commissioner, "The challenge to regulators and industry is to keep this disease out of the United States. One important defense is to prohibit the use of any ruminant animal materials in feed for other ruminant animals. Combined with other steps, like U.S. Department of Agriculture's (USDA) ban on the importation of live ruminant animals from affected countries, these steps represent a series of protections, to keep American cattle free of BSE."</p><p> </p><p>Despite this negligible risk, Purina Mills, Inc., is nonetheless announcing that it is voluntarily purchasing all 1,222 of the animals held in Texas and mistakenly fed the animal feed containing the prohibited material. Therefore, meat from those animals will not enter the human food supply. FDA believes any cattle that did not consume feed containing the prohibited material are unaffected by this incident, and should be handled in the beef supply clearance process as usual.</p><p> </p><p>FDA believes that Purina Mills has behaved responsibly by first reporting the human error that resulted in the misformulation of the animal feed supplement and then by working closely with State and Federal authorities.</p><p> </p><p>This episode indicates that the multi-layered safeguard system put into place is essential for protecting the food supply and that continued vigilance needs to be taken, by all concerned, to ensure these rules are followed routinely.</p><p> </p><p>FDA will continue working with USDA as well as State and local officials to ensure that companies and individuals comply with all laws and regulations designed to protect the U.S. food supply.</p><p> </p><p><a href="http://www.fda.gov/bbs/topics/NEWS/2001/NEW00752.html" target="_blank">http://www.fda.gov/bbs/topics/NEWS/2001/NEW00752.html</a></p><p> </p><p>NEWS RELEASE</p><p> </p><p>Texas Animal Health Commission</p><p> </p><p>Box l2966 •Austin, Texas 78711 •(800) 550-8242• FAX (512) 719-0719</p><p> </p><p>Linda Logan, DVM, PhD• Executive Director</p><p> </p><p>For info, contact Carla Everett, information officer, at 1-800-550-8242, ext. 710,</p><p> </p><p>or <a href="mailto:ceverett@tahc.state.tx.us">ceverett@tahc.state.tx.us</a></p><p> </p><p>For Immediate Release--</p><p> </p><p>Feed Contamination Issue Resolved by FDA</p><p> </p><p>Although many of you may have heard the latest regarding the resolution of the cattle feed contamination situation in Texas, I wanted to ensure that you received this statement issued by the Food and Drug Administration (FDA), the agency in charge of regulating feed components. The FDA has said the cattle involved are to be rendered and the material will not enter ruminant or human food channels. The Texas Animal Health Commission (TAHC) will provided assistance to the FDA as requested and needed.</p><p> </p><p>FDA ANNOUNCES TEST RESULTS FROM TEXAS FEED LOT</p><p> </p><p>Today (Tuesday, Jan. the Food and Drug Administration announced the results of tests taken on feed used at a Texas feedlot that was suspected of containing meat and bone meal from other domestic cattle -- a violation of FDA's 1997 prohibition on using ruminant material in feed for other ruminants. Results indicate that a very low level of prohibited material was found in the feed fed to cattle.</p><p> </p><p>FDA has determined that each animal could have consumed, at most and in total, five-and-one-half grams - approximately a quarter ounce -- of prohibited material. These animals weigh approximately 600 pounds.</p><p> </p><p>It is important to note that the prohibited material was domestic in origin (therefore not likely to contain infected material because there is no evidence of BSE in U.S. cattle), fed at a very low level, and fed only once. The potential risk of BSE to such cattle is therefore exceedingly low, even if the feed were contaminated.</p><p> </p><p>According to Dr. Bernard Schwetz, FDA's Acting Principal Deputy Commissioner, "The challenge to regulators and industry is to keep this disease out of the United States. One important defense is to prohibit the use of any ruminant animal materials in feed for other ruminant animals. Combined with other steps, like U.S. Department of Agriculture's (USDA) ban on the importation of live ruminant animals from affected countries, these steps represent a series of protections, to keep American cattle free of BSE."</p><p> </p><p>Despite this negligible risk, Purina Mills, Inc., is nonetheless announcing that it is voluntarily purchasing all 1,222 of the animals held in Texas and mistakenly fed the animal feed containing the prohibited material. Therefore, meat from those animals will not enter the human food supply. FDA believes any cattle that did not consume feed containing the prohibited material are unaffected by this incident, and should be handled in the beef supply clearance process as usual.</p><p> </p><p>FDA believes that Purina Mills has behaved responsibly by first reporting the human error that resulted in the misformulation of the animal feed supplement and then by working closely with State and Federal authorities. This episode indicates that the multi-layered safeguard system put into place is essential for protecting the food supply and that continued vigilance needs to be taken, by all concerned, to ensure these rules are followed routinely.</p><p> </p><p>FDA will continue working with USDA as well as state and local officials to ensure that</p><p> </p><p>companies and individuals comply with all laws and regulations designed to protect the U.S.</p><p> </p><p>food supply.</p><p> </p><p>---30--</p><p> </p><p><a href="http://www.tahc.state.tx.us/News/pr/2001/101FEED_ISSUE_RESOLVED.pdf" target="_blank">http://www.tahc.state.tx.us/News/pr/200 ... SOLVED.pdf</a></p><p> </p><p> </p><p>WE know now, and we knew decades ago, that 5.5 grams of suspect feed in TEXAS was enough to kill 100 cows.</p><p> </p><p>look at the table and you'll see that as little as 1 mg (or 0.001 gm) caused 7% (1 of 14) of the cows to come down with BSE;</p><p> </p><p>Risk of oral infection with bovine spongiform encephalopathy agent in primates</p><p> </p><p>Corinne Ida Lasmézas, Emmanuel Comoy, Stephen Hawkins, Christian Herzog, Franck Mouthon, Timm Konold, Frédéric Auvré, Evelyne Correia, Nathalie Lescoutra-Etchegaray, Nicole Salès, Gerald Wells, Paul Brown, Jean-Philippe Deslys Summary The uncertain extent of human exposure to bovine spongiform encephalopathy (BSE)--which can lead to variant Creutzfeldt-Jakob disease (vCJD)--is compounded by incomplete knowledge about the efficiency of oral infection and the magnitude of any bovine-to-human biological barrier to transmission. We therefore investigated oral transmission of BSE to non-human primates. We gave two macaques a 5 g oral dose of brain homogenate from a BSE-infected cow. One macaque developed vCJD-like neurological disease 60 months after exposure, whereas the other remained free of disease at 76 months. On the basis of these findings and data from other studies, we made a preliminary estimate of the food exposure risk for man, which provides additional assurance that existing public health measures can prevent transmission of BSE to man.</p><p> </p><p>snip...</p><p> </p><p>BSE bovine brain inoculum</p><p> </p><p>100 g 10 g 5 g 1 g 100 mg 10 mg 1 mg 0·1 mg 0·01 mg</p><p> </p><p>Primate (oral route)* 1/2 (50%)</p><p> </p><p>Cattle (oral route)* 10/10 (100%) 7/9 (78%) 7/10 (70%) 3/15 (20%) 1/15 (7%) 1/15 (7%)</p><p> </p><p>RIII mice (ic ip route)* 17/18 (94%) 15/17 (88%) 1/14 (7%)</p><p> </p><p>PrPres biochemical detection</p><p> </p><p>The comparison is made on the basis of calibration of the bovine inoculum used in our study with primates against a bovine brain inoculum with a similar PrPres concentration that was inoculated into mice and cattle.8 *Data are number of animals positive/number of animals surviving at the time of clinical onset of disease in the first positive animal (%). The accuracy of bioassays is generally judged to be about plus or minus 1 log. ic ip=intracerebral and intraperitoneal.</p><p> </p><p>Table 1: Comparison of transmission rates in primates and cattle infected orally with similar BSE brain inocula</p><p> </p><p>Published online January 27, 2005</p><p> </p><p><a href="http://www.thelancet.com/journal/journal.isa" target="_blank">http://www.thelancet.com/journal/journal.isa</a> </p><p> </p><p>Sunday, December 15, 2013 </p><p> </p><p>*** FDA PART 589 -- SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEED VIOLATIONS OFFICIAL ACTION INDICATED OIA UPDATE DECEMBER 2013 UPDATE ***</p><p> </p><p><a href="http://madcowusda.blogspot.com/2013/12/fda-part-589-substances-prohibited-from.html" target="_blank">http://madcowusda.blogspot.com/2013/12/ ... -from.html</a></p></blockquote><p></p>
[QUOTE="flounder, post: 1140605, member: 3519"] [url=http://madcowusda.blogspot.com/2012_06_01_archive.html]http://madcowusda.blogspot.com/2012_06_01_archive.html[/url] FDA MAD COW FEED BAN NOTHING BUT INK ON PAPER Note: On Dec. 23, 2003, the U.S. Department of Agriculture reported that a cow in Washington state had tested positive for bovine spongiform encephalopathy (BSE, or mad cow disease). As a result, information on this Web page stating that no BSE cases had been found in the United States is now incorrect. However, because other information on this page continues to have value, the page will remain available for viewing. FDA ANNOUNCES TEST RESULTS FROM TEXAS FEED LOT Today the Food and Drug Administration announced the results of tests taken on feed used at a Texas feedlot that was suspected of containing meat and bone meal from other domestic cattle -- a violation of FDA's 1997 prohibition on using ruminant material in feed for other ruminants. Results indicate that a very low level of prohibited material was found in the feed fed to cattle. FDA has determined that each animal could have consumed, at most and in total, five-and-one-half grams - approximately a quarter ounce -- of prohibited material. These animals weigh approximately 600 pounds. It is important to note that the prohibited material was domestic in origin (therefore not likely to contain infected material because there is no evidence of BSE in U.S. cattle), fed at a very low level, and fed only once. The potential risk of BSE to such cattle is therefore exceedingly low, even if the feed were contaminated. According to Dr. Bernard Schwetz, FDA's Acting Principal Deputy Commissioner, "The challenge to regulators and industry is to keep this disease out of the United States. One important defense is to prohibit the use of any ruminant animal materials in feed for other ruminant animals. Combined with other steps, like U.S. Department of Agriculture's (USDA) ban on the importation of live ruminant animals from affected countries, these steps represent a series of protections, to keep American cattle free of BSE." Despite this negligible risk, Purina Mills, Inc., is nonetheless announcing that it is voluntarily purchasing all 1,222 of the animals held in Texas and mistakenly fed the animal feed containing the prohibited material. Therefore, meat from those animals will not enter the human food supply. FDA believes any cattle that did not consume feed containing the prohibited material are unaffected by this incident, and should be handled in the beef supply clearance process as usual. FDA believes that Purina Mills has behaved responsibly by first reporting the human error that resulted in the misformulation of the animal feed supplement and then by working closely with State and Federal authorities. This episode indicates that the multi-layered safeguard system put into place is essential for protecting the food supply and that continued vigilance needs to be taken, by all concerned, to ensure these rules are followed routinely. FDA will continue working with USDA as well as State and local officials to ensure that companies and individuals comply with all laws and regulations designed to protect the U.S. food supply. [url=http://www.fda.gov/bbs/topics/NEWS/2001/NEW00752.html]http://www.fda.gov/bbs/topics/NEWS/2001/NEW00752.html[/url] NEWS RELEASE Texas Animal Health Commission Box l2966 •Austin, Texas 78711 •(800) 550-8242• FAX (512) 719-0719 Linda Logan, DVM, PhD• Executive Director For info, contact Carla Everett, information officer, at 1-800-550-8242, ext. 710, or [email=ceverett@tahc.state.tx.us]ceverett@tahc.state.tx.us[/email] For Immediate Release-- Feed Contamination Issue Resolved by FDA Although many of you may have heard the latest regarding the resolution of the cattle feed contamination situation in Texas, I wanted to ensure that you received this statement issued by the Food and Drug Administration (FDA), the agency in charge of regulating feed components. The FDA has said the cattle involved are to be rendered and the material will not enter ruminant or human food channels. The Texas Animal Health Commission (TAHC) will provided assistance to the FDA as requested and needed. FDA ANNOUNCES TEST RESULTS FROM TEXAS FEED LOT Today (Tuesday, Jan. the Food and Drug Administration announced the results of tests taken on feed used at a Texas feedlot that was suspected of containing meat and bone meal from other domestic cattle -- a violation of FDA's 1997 prohibition on using ruminant material in feed for other ruminants. Results indicate that a very low level of prohibited material was found in the feed fed to cattle. FDA has determined that each animal could have consumed, at most and in total, five-and-one-half grams - approximately a quarter ounce -- of prohibited material. These animals weigh approximately 600 pounds. It is important to note that the prohibited material was domestic in origin (therefore not likely to contain infected material because there is no evidence of BSE in U.S. cattle), fed at a very low level, and fed only once. The potential risk of BSE to such cattle is therefore exceedingly low, even if the feed were contaminated. According to Dr. Bernard Schwetz, FDA's Acting Principal Deputy Commissioner, "The challenge to regulators and industry is to keep this disease out of the United States. One important defense is to prohibit the use of any ruminant animal materials in feed for other ruminant animals. Combined with other steps, like U.S. Department of Agriculture's (USDA) ban on the importation of live ruminant animals from affected countries, these steps represent a series of protections, to keep American cattle free of BSE." Despite this negligible risk, Purina Mills, Inc., is nonetheless announcing that it is voluntarily purchasing all 1,222 of the animals held in Texas and mistakenly fed the animal feed containing the prohibited material. Therefore, meat from those animals will not enter the human food supply. FDA believes any cattle that did not consume feed containing the prohibited material are unaffected by this incident, and should be handled in the beef supply clearance process as usual. FDA believes that Purina Mills has behaved responsibly by first reporting the human error that resulted in the misformulation of the animal feed supplement and then by working closely with State and Federal authorities. This episode indicates that the multi-layered safeguard system put into place is essential for protecting the food supply and that continued vigilance needs to be taken, by all concerned, to ensure these rules are followed routinely. FDA will continue working with USDA as well as state and local officials to ensure that companies and individuals comply with all laws and regulations designed to protect the U.S. food supply. ---30-- [url=http://www.tahc.state.tx.us/News/pr/2001/101FEED_ISSUE_RESOLVED.pdf]http://www.tahc.state.tx.us/News/pr/200 ... SOLVED.pdf[/url] WE know now, and we knew decades ago, that 5.5 grams of suspect feed in TEXAS was enough to kill 100 cows. look at the table and you'll see that as little as 1 mg (or 0.001 gm) caused 7% (1 of 14) of the cows to come down with BSE; Risk of oral infection with bovine spongiform encephalopathy agent in primates Corinne Ida Lasmézas, Emmanuel Comoy, Stephen Hawkins, Christian Herzog, Franck Mouthon, Timm Konold, Frédéric Auvré, Evelyne Correia, Nathalie Lescoutra-Etchegaray, Nicole Salès, Gerald Wells, Paul Brown, Jean-Philippe Deslys Summary The uncertain extent of human exposure to bovine spongiform encephalopathy (BSE)--which can lead to variant Creutzfeldt-Jakob disease (vCJD)--is compounded by incomplete knowledge about the efficiency of oral infection and the magnitude of any bovine-to-human biological barrier to transmission. We therefore investigated oral transmission of BSE to non-human primates. We gave two macaques a 5 g oral dose of brain homogenate from a BSE-infected cow. One macaque developed vCJD-like neurological disease 60 months after exposure, whereas the other remained free of disease at 76 months. On the basis of these findings and data from other studies, we made a preliminary estimate of the food exposure risk for man, which provides additional assurance that existing public health measures can prevent transmission of BSE to man. snip... BSE bovine brain inoculum 100 g 10 g 5 g 1 g 100 mg 10 mg 1 mg 0·1 mg 0·01 mg Primate (oral route)* 1/2 (50%) Cattle (oral route)* 10/10 (100%) 7/9 (78%) 7/10 (70%) 3/15 (20%) 1/15 (7%) 1/15 (7%) RIII mice (ic ip route)* 17/18 (94%) 15/17 (88%) 1/14 (7%) PrPres biochemical detection The comparison is made on the basis of calibration of the bovine inoculum used in our study with primates against a bovine brain inoculum with a similar PrPres concentration that was inoculated into mice and cattle.8 *Data are number of animals positive/number of animals surviving at the time of clinical onset of disease in the first positive animal (%). The accuracy of bioassays is generally judged to be about plus or minus 1 log. ic ip=intracerebral and intraperitoneal. Table 1: Comparison of transmission rates in primates and cattle infected orally with similar BSE brain inocula Published online January 27, 2005 [url=http://www.thelancet.com/journal/journal.isa]http://www.thelancet.com/journal/journal.isa[/url] Sunday, December 15, 2013 *** FDA PART 589 -- SUBSTANCES PROHIBITED FROM USE IN ANIMAL FOOD OR FEED VIOLATIONS OFFICIAL ACTION INDICATED OIA UPDATE DECEMBER 2013 UPDATE *** [url=http://madcowusda.blogspot.com/2013/12/fda-part-589-substances-prohibited-from.html]http://madcowusda.blogspot.com/2013/12/ ... -from.html[/url] [/QUOTE]
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TEXAS CONFIRMED HUMAN BSE VCJD IN ADULT MALE
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