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<blockquote data-quote="Lucky_P" data-source="post: 988965" data-attributes="member: 12607"><p>Nice overview of neosporosis from UofWI here: <a href="http://www.wvdl.wisc.edu/PDF%5CWVDL.Info.Recognizing_and_Preventing_Neosporosis_Infections.pdf" target="_blank">http://www.wvdl.wisc.edu/PDF%5CWVDL.Inf ... ctions.pdf</a></p><p>Lots of info on the 'net about it. </p><p>Has been implicated as a leading cause of abortion in dairy cattle on the left coast, and in the northeastern US.</p><p>I've been looking for it in virtually every aborted/stillborn calf I've looked at for nearly 25 years; up until a couple of years ago, had only seen a handful of cases, but we are finding it more frequently over the last 2-3 years.</p><p></p><p>There is division of opinion within the veterinary diagnostic community about it. </p><p>For instance, in the calf I necropsied last week - no lesions whatsoever to suggest Neospora infection - but they picked it up with PCR. We know that a significant percentage of cattle infected with N. caninum give birth to clinically normal, but infected calves; usually, if they go to term, they will be 'normal' in all respects, but infected heifers may abort when they reach breeding age, or give birth to another generation of infected but clinically normal calves. </p><p>So... does a positive PCR result, in the face of no gross or microscopic lesions, really incriminate Neospora - or any other pathogen - as the cause of abortion/stillbirth/perinatal death? That's a question I struggle with every day; even when I find brain lesions, they are so tiny and localized, that I sometimes wonder if they're really the cause of fetal death and abortion. But identifying its presence - in the absence of other pathogens - is, at least a presumptive diagnosis, and gives the producer and their veterinarian a windmill to tilt at, if nothing else.</p></blockquote><p></p>
[QUOTE="Lucky_P, post: 988965, member: 12607"] Nice overview of neosporosis from UofWI here: [url=http://www.wvdl.wisc.edu/PDF%5CWVDL.Info.Recognizing_and_Preventing_Neosporosis_Infections.pdf]http://www.wvdl.wisc.edu/PDF%5CWVDL.Inf ... ctions.pdf[/url] Lots of info on the 'net about it. Has been implicated as a leading cause of abortion in dairy cattle on the left coast, and in the northeastern US. I've been looking for it in virtually every aborted/stillborn calf I've looked at for nearly 25 years; up until a couple of years ago, had only seen a handful of cases, but we are finding it more frequently over the last 2-3 years. There is division of opinion within the veterinary diagnostic community about it. For instance, in the calf I necropsied last week - no lesions whatsoever to suggest Neospora infection - but they picked it up with PCR. We know that a significant percentage of cattle infected with N. caninum give birth to clinically normal, but infected calves; usually, if they go to term, they will be 'normal' in all respects, but infected heifers may abort when they reach breeding age, or give birth to another generation of infected but clinically normal calves. So... does a positive PCR result, in the face of no gross or microscopic lesions, really incriminate Neospora - or any other pathogen - as the cause of abortion/stillbirth/perinatal death? That's a question I struggle with every day; even when I find brain lesions, they are so tiny and localized, that I sometimes wonder if they're really the cause of fetal death and abortion. But identifying its presence - in the absence of other pathogens - is, at least a presumptive diagnosis, and gives the producer and their veterinarian a windmill to tilt at, if nothing else. [/QUOTE]
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