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<blockquote data-quote="Lucky_P" data-source="post: 1522561" data-attributes="member: 12607"><p>Calves' immune system 'tanks' from about days 3 to 7; if you're gonna give anything, do it on Day One, or wait 'til they're 10 days or older. </p><p></p><p>I just attended a veterinary meeting last week, with major emphasis on immunity and vaccination. Based on the information presented there:</p><p>Only really 'safe' and effective vaccines that you should give calves in 1st week of life... intranasal respiratory vaccines like Inforce-3 or Nasalgen, C.perfringens C&D toxoid if 'overeating disease' is a problem in your herd. Any others... wait until the calves are at least 60 days of age. Maternal (colostral) antibodies have been shown to prevent response to the Clostridial bacterins at least for the first couple of months. </p><p></p><p>In general, intranasal mlv vaccines do not interfere with response to bacterins... but injectible mlv IBR vaccines will block immune response to bacterins administered at the same time... unless the animals have had a 'priming' dose of intranasal IBR administered previously (and recently).</p><p></p><p>Calves immune systems are not 'mature' until 10-12 months of age... so, if you're setting up heifers for pre-breeding fetal protection vaccinations... you need to do that as yearlings... mlv vaccines administered prior to or at weaning will not provide the desired protection.</p></blockquote><p></p>
[QUOTE="Lucky_P, post: 1522561, member: 12607"] Calves' immune system 'tanks' from about days 3 to 7; if you're gonna give anything, do it on Day One, or wait 'til they're 10 days or older. I just attended a veterinary meeting last week, with major emphasis on immunity and vaccination. Based on the information presented there: Only really 'safe' and effective vaccines that you should give calves in 1st week of life... intranasal respiratory vaccines like Inforce-3 or Nasalgen, C.perfringens C&D toxoid if 'overeating disease' is a problem in your herd. Any others... wait until the calves are at least 60 days of age. Maternal (colostral) antibodies have been shown to prevent response to the Clostridial bacterins at least for the first couple of months. In general, intranasal mlv vaccines do not interfere with response to bacterins... but injectible mlv IBR vaccines will block immune response to bacterins administered at the same time... unless the animals have had a 'priming' dose of intranasal IBR administered previously (and recently). Calves immune systems are not 'mature' until 10-12 months of age... so, if you're setting up heifers for pre-breeding fetal protection vaccinations... you need to do that as yearlings... mlv vaccines administered prior to or at weaning will not provide the desired protection. [/QUOTE]
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