For unbiased information on bse and cdj look here

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hooknline said:
This site has a pretty comprehensive overview of bse, it's causes, timeframes, implications, and affect on humans ( aka cjd)
Figured I'd post it to counter chicken littles posts on the subject. If info is ging to be spread, it might as well be accurate and unbiased as possible



snip...end





:lol2: :lol2:


the data there is about 30 years outdated...


please understand, sporadic cjd is not a single strain of CJD/TSE. sporadic CJD means many strains of CJD, simply meaning the routes and sources there from i.e. the causes, are unknown. all iatrogenic CJD is, is sporadic CJD, until the route and source is confirmed, and there are many here in the USA, from many different TSE prion disease in many different species. the strains are growing too. we have typical and atypical TSE prion disease in both man and animal in North America, and the list continues to grow, the TSE prion strains continue to become more virulent in some strains. friendly fire there from, is most disturbing. also, sporadic CJD has now been linked to some strains of atypical BSE and atypical Scrapie. please see ;






Thursday, August 12, 2010

Seven main threats for the future linked to prions

First threat

The TSE road map defining the evolution of European policy for protection against prion diseases is based on a certain numbers of hypotheses some of which may turn out to be erroneous. In particular, a form of BSE (called atypical Bovine Spongiform Encephalopathy), recently identified by systematic testing in aged cattle without clinical signs, may be the origin of classical BSE and thus potentially constitute a reservoir, which may be impossible to eradicate if a sporadic origin is confirmed. ***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.

Second threat

snip...

http://www.neuroprion.org/en/np-neuroprion.html




EFSA Journal 2011 The European Response to BSE: A Success Story

This is an interesting editorial about the Mad Cow Disease debacle, and it's ramifications that will continue to play out for decades to come ;

Monday, October 10, 2011

EFSA Journal 2011 The European Response to BSE: A Success Story

snip...

EFSA and the European Centre for Disease Prevention and Control (ECDC) recently delivered a scientific opinion on any possible epidemiological or molecular association between TSEs in animals and humans (EFSA Panel on Biological Hazards (BIOHAZ) and ECDC, 2011). This opinion confirmed Classical BSE prions as the only TSE agents demonstrated to be zoonotic so far but the possibility that a small proportion of human cases so far classified as "sporadic" CJD are of zoonotic origin could not be excluded. Moreover, transmission experiments to non-human primates suggest that some TSE agents in addition to Classical BSE prions in cattle (namely L-type Atypical BSE, Classical BSE in sheep, transmissible mink encephalopathy (TME) and chronic wasting disease (CWD) agents) might have zoonotic potential.

snip...



http://www.efsa.europa.eu/en/efsajourna ... .htm?emt=1



http://www.efsa.europa.eu/en/efsajournal/doc/e991.pdf



see follow-up here about North America BSE Mad Cow TSE prion risk factors, and the ever emerging strains of Transmissible Spongiform Encephalopathy in many species here in the USA, including humans ;

http://transmissiblespongiformencephalo ... se-to.html




2010-2011

When L-type BSE was inoculated into ovine transgenic mice and Syrian hamster the resulting molecular fingerprint had changed, either in the first or a subsequent passage, from L-type into C-type BSE. In addition, non-human primates are specifically susceptible for atypical BSE as demonstrated by an approximately 50% shortened incubation time for L-type BSE as compared to C-type. Considering the current scientific information available, it cannot be assumed that these different BSE types pose the same human health risks as C-type BSE or that these risks are mitigated by the same protective measures.

This study will contribute to a correct definition of specified risk material (SRM) in atypical BSE. The incumbent of this position will develop new and transfer existing, ultra-sensitive methods for the detection of atypical BSE in tissue of experimentally infected cattle.



http://www.prionetcanada.ca/detail.aspx ... lk=no&cat2



Monday, July 23, 2012

The National Prion Disease Pathology Surveillance Center July 2012

http://prionunitusaupdate2008.blogspot. ... ology.html




tss
 
Monday, August 6, 2012

TAFS BSE in USA August 6, 2012

BSE in USA

http://bseusa.blogspot.com/2012/08/tafs ... -2012.html



Monday, August 06, 2012

Atypical neuropathological sCJD-MM phenotype with abundant white matter Kuru-type plaques sparing the cerebellar cortex

http://creutzfeldt-jakob-disease.blogsp ... jd-mm.html



Wednesday, August 01, 2012

Behavioural and Psychiatric Features of the Human Prion Diseases: Experience in 368 Prospectively Studied Patients

http://creutzfeldt-jakob-disease.blogsp ... es-of.html




Tuesday, June 26, 2012

Creutzfeldt Jakob Disease Human TSE report update North America, Canada, Mexico, and USDA PRION UNIT as of May 18, 2012

type determination pending Creutzfeldt Jakob Disease (tdpCJD), is on the rise in Canada and the USA

http://creutzfeldt-jakob-disease.blogsp ... n-tse.html




all iatrogenic creutzfeldt jakob disease is, is sporadic creutzfeldt jakob disease, until route and source is proven $$$


Friday, August 24, 2012

Iatrogenic prion diseases in humans: an update

http://transmissiblespongiformencephalo ... umans.html



kind regards,
terry
 
The article I linked was revised in 2002. Far short of 30 years.
Your links posted are 80% blogs. Much like cattletoday.
Much of which is opinion and conjecture, sometimes accurate and sometimes way off the mark. Your links and are also a bunch of fear mongering one sided posts with very little actual evidence to back it up. Very few studies, links to facts, just a bunch of articles posting supposition.
I don't mind reading facts. I despise fear mongering for whatever purpose you see fit.
Which brings me to my next question for you, what exactly is the goal you hope to Achieve with your posts?
I doubt you are just looking to spread information. I suspect you are trying to spread fear for a purpose you have not yet made clear.
Do me a favor, make it clear. What's the purpose behind your posts that are all about bse?
 
Notice the heading on the links in your first response. EDITORIAL. Now just in case you didn't know, that means OPINION
 
hooknline":yqrbmzii said:
Notice the heading on the links in your first response. EDITORIAL. Now just in case you didn't know, that means OPINION


PO-028: Oral transmission of L-type bovine spongiform encephalopathy (L-BSE) in primate model Microcebus murinus


Nadine Mestre-Frances,1 Simon Nicot,2 Sylvie Rouland,1 Anne-Gaëlle Biacabe,2 Isabelle Quadrio,3 Armand Perret-Liaudet,3 Thierry Baron,2 Jean-Michel Verdier1
1IN SER M UM2; Montpellier, France; 2Anses; Lyon, France; 3Hopitaux Civils de Lyon; Lyon, France

An atypical form of bovine spongiform encephalopathy has been identified in cattle in Europe, North America and Japan and was designed as L-type BSE (L-BSE) due to the lower apparent molecular mass of the unglycosylated, protease-resistant prion protein (PrPres) detected by western blot compared with classical BSE. Experimental evidences from studies in transgenic mice expressing human PrP and in primate models suggest a higher risk of transmission to humans of the L-BSE form than for classical BSE agent. However, a major unresolved issue concerns the potential transmissibility of the L-BSE agent by oral route. To address this question, we infected mouse lemurs (Microcebus murinus), a non-human primate model, with L-BSE by intracerebral or oral route.

Four adult lemurs were intracerebrally (IC) inoculated with 5mg of L-BSE infected brain homogenate of an atypical French BSE case (02-2528). Four young and four adult animals were fed with 5 mg or 50 mg of infected brain. After sacrifice, the brain tissues were biochemically and immunocytochemically investigated for PrPres.

The 4 animals IC inoculated died at 19 and 22 months postinoculation (mpi). They developed blindness, tremor, abnormal posture, incoordinated movements, balance loss. Symptoms get worse according to the disease progression, until severe ataxia. Severe spongiosis was evidenced into the thalamus, the striatum, the mesencephalon, and the brainstem, whereas into the cortex the vacuolisation was weaker. Strong deposits of PrPres were detected into the thalamus, the striatum, and the hippocampus whereas in the cerebral cortex, PrPres was prominently accumulated in plaques.

The orally inoculated animals showed similar clinical symptoms occurring between 27 and 34 mpi. Disease was characterized by progressive prostration, loss of appetite and poor appearance of the fur. Only one adult animal showed disequilibrium. PrPres was strongly accumulated only in the striatum and thalamus and weakly into the cortex. No plaques were evidenced. Two animals that were orally challenged at the age of two years are still alive and healthy 34 months after inoculation. The western blot analysis showed uniform molecular profiles, irrespective of the route or dose of infection, and included notably a PrPres form with low apparent molecular mass (~19 kDa) similar to the PrPres in the original cattle brain. However, the PrPres profile in lemurs was characterized by a higher proportion of di- and mono-glycosylated species (up to 95% of the total signal) than in the bovine L-BSE inoculum (~80%). In addition, small amounts of PrPres were detected by western blotting in the spleen of three animals (one intra-cerebrally inoculated and two fed with 5 mg of cattle brain).

Here, we demonstrate that the L-BSE agent can be transmitted by oral route from cattle to young and adult mouse lemurs. In comparison to IC inoculated animals, orally challenged lemurs were characterized by longer survival periods as expected with this route of infection.




http://www.landesbioscience.com/journal ... trains.pdf






***Also, a link is suspected between atypical BSE and some apparently sporadic cases of Creutzfeldt-Jakob disease in humans. These atypical BSE cases constitute an unforeseen first threat that could sharply modify the European approach to prion diseases.

Second threat

snip...


http://www.neuroprion.org/en/np-neuroprion.html



MAD COW USDA ATYPICAL L-TYPE BASE BSE, the rest of the story...


***Oral Transmission of L-type Bovine Spongiform Encephalopathy in Primate Model



http://wwwnc.cdc.gov/eid/article/18/1/pdfs/11-1092.pdf



***Infectivity in skeletal muscle of BASE-infected cattle



http://www.neuroprion.org/resources/pdf ... tracts.pdf



***feedstuffs- It also suggests a similar cause or source for atypical BSE in these countries.



http://www.neuroprion.org/resources/pdf ... tracts.pdf



The present study demonstrated successful intraspecies transmission of H-type BSE to cattle and the distribution and immunolabeling patterns of PrPSc in the brain of the H-type BSE-challenged cattle. TSE agent virulence can be minimally defined by oral transmission of different TSE agents (C-type, L-type, and H-type BSE agents) [59]. Oral transmission studies with H-type BSEinfected cattle have been initiated and are underway to provide information regarding the extent of similarity in the immunohistochemical and molecular features before and after transmission.

In addition, the present data will support risk assessments in some peripheral tissues derived from cattle affected with H-type BSE.


http://www.veterinaryresearch.org/conte ... -42-79.pdf



kind regards,
terry
 
Sorry flounder. Myself and I'm sure a lot of others aren't even reading half the bullshyt you post. I try, I really do. But most everything i see from you is one sided fear mongering.

PlEase answer my question: what is the purpose of your posts?
It sure isn't just to spread information and facts otherwise you wouldnt bother to post links to opines.
 
hooknline":ix9ajdt2 said:
Sorry flounder. Myself and I'm sure a lot of others aren't even reading half the bullshyt you post. I try, I really do. But most everything i see from you is one sided fear mongering.

PlEase answer my question: what is the purpose of your posts?
It sure isn't just to spread information and facts otherwise you wouldnt bother to post links to opines.



i have already answered your question, but if you did not understand it the first two times, here it is one more time ;



test, test, test. ...



p.s. the reason of my post was to refute the BSe that you had posted, that was sooo outdated. ...



have a great day...



kind regards,
terry
 
Yep. More obtuse reponse from the cut and paste expert

Is your argument that the testing and procedures and protocols in place already are not doing the job? Because evey case in point you point out proves that they indeed doing the job. Otherwise you wouldn't even be able to cut and paste about them. They wouldn't even be on a blog much less a news article
 
hooknline":1b85a3bu said:
Yep. More obtuse reponse from the cut and paste expert

Is your argument that the testing and procedures and protocols in place already are not doing the job? Because evey case in point you point out proves that they indeed doing the job. Otherwise you wouldn't even be able to cut and paste about them. They wouldn't even be on a blog much less a news article




:lol2: :lol2:





USDA INC. BSE surveillance


this also was a complete failure as well, to a point that the GAO caught the USDA et al in their BSE testing surveillance program, red handed testing cattle they knew were healthy, free of BSE. yes, up to 100 farms testing for mad cow disease, but the animals in question, were all healthy animal brains, and they knew it. but that was not the only failures in the BSE testing program, that was just part of it. the USDA covered up two mad cows in Texas, one finally confirmed after an act of Congress by the OIG made the USDA retest that cow, some 7 months later, and finally confirm, what they already knew with a SECRET test that had tested positive 7 months previously, and finally were forced to confirm this second mad cow in Texas. it got so bad around 2005, that the top prion scientist at the NIH Paul Brown, said "Everything they did on the Texas cow makes everything they did before 2005 suspect," Brown said.


http://www.upi.com/Health_News/2006/03/ ... 142465253/



NOW, what about that mad cow BSE surveillance and testing program ???



PAUL BROWN COMMENT TO ME ON THIS ISSUE




Tuesday, September 12, 2006 11:10 AM




"Actually, Terry, I have been critical of the USDA handling of the mad cow issue for some years, and with Linda Detwiler and others sent lengthy detailed critiques and recommendations to both the USDA and the Canadian Food Agency."




OR, what the Honorable Phyllis Fong of the OIG found ;




Audit Report




Animal and Plant Health Inspection Service




Bovine Spongiform Encephalopathy (BSE) Surveillance Program – Phase II




and




Food Safety and Inspection Service




Controls Over BSE Sampling, Specified Risk Materials, and Advanced Meat Recovery Products - Phase III




Report No. 50601-10-KC January 2006




Finding 2 Inherent Challenges in Identifying and Testing High-Risk Cattle Still Remain




http://www.usda.gov/oig/webdocs/50601-10-KC.pdf


http://madcowtesting.blogspot.com/2009/ ... es-in.html




Subject: USDA OIG SEMIANNUAL REPORT TO CONGRESS FY 2007 1st Half (bogus BSE sampling FROM HEALTHY USDA CATTLE) Date: June 21, 2007 at 2:49 pm PST




Owner and Corporation Plead Guilty to Defrauding Bovine Spongiform Encephalopathy (BSE) Surveillance Program




An Arizona meat processing company and its owner pled guilty in February 2007 to charges of theft of Government funds, mail fraud, and wire fraud. The owner and his company defrauded the BSE Surveillance Program when they falsified BSE Surveillance Data Collection Forms and then submitted payment requests to USDA for the services. In addition to the targeted sample population (those cattle that were more than 30 months old or had other risk factors for BSE), the owner submitted to USDA, or caused to be submitted, BSE obex (brain stem) samples from healthy USDA-inspected cattle. As a result, the owner fraudulently received approximately $390,000. Sentencing is scheduled for May 2007.




snip...




Topics that will be covered in ongoing or planned reviews under Goal 1 include:




soundness of BSE maintenance sampling (APHIS),




implementation of Performance-Based Inspection System enhancements for specified risk material (SRM) violations and improved inspection controls over SRMs (FSIS and APHIS),




snip...




The findings and recommendations from these efforts will be covered in future semiannual reports as the relevant audits and investigations are completed.




4 USDA OIG SEMIANNUAL REPORT TO CONGRESS FY 2007 1st Half




http://www.usda.gov/oig/webdocs/sarc070619.pdf




-MORE Office of the United States Attorney District of Arizona FOR IMMEDIATE RELEASE For Information Contact Public Affairs February 16, 2007 WYN HORNBUCKLE Telephone: (602) 514-7625 Cell: (602) 525-2681




CORPORATION AND ITS PRESIDENT PLEAD GUILTY TO DEFRAUDING GOVERNMENT'S MAD COW DISEASE SURVEILLANCE PROGRAM




PHOENIX -- Farm Fresh Meats, Inc. and Roland Emerson Farabee, 55, of Maricopa, Arizona, pleaded guilty to stealing $390,000 in government funds, mail fraud and wire fraud, in federal district court in Phoenix. U.S. Attorney Daniel Knauss stated, "The integrity of the system that tests for mad cow disease relies upon the honest cooperation of enterprises like Farm Fresh Meats. Without that honest cooperation, consumers both in the U.S. and internationally are at risk. We want to thank the USDA's Office of Inspector General for their continuing efforts to safeguard the public health and enforce the law." Farm Fresh Meats and Farabee were charged by Information with theft of government funds, mail fraud and wire fraud. According to the Information, on June 7, 2004, Farabee, on behalf of Farm Fresh Meats, signed a contract with the U.S. Department of Agriculture (the "USDA Agreement") to collect obex samples from cattle at high risk of mad cow disease (the "Targeted Cattle Population"). The Targeted Cattle Population consisted of the following cattle: cattle over thirty months of age; nonambulatory cattle; cattle exhibiting signs of central nervous system disorders; cattle exhibiting signs of mad cow disease; and dead cattle. Pursuant to the USDA Agreement, the USDA agreed to pay Farm Fresh Meats $150 per obex sample for collecting obex samples from cattle within the Targeted Cattle Population, and submitting the obex samples to a USDA laboratory for mad cow disease testing. Farm Fresh Meats further agreed to maintain in cold storage the sampled cattle carcasses and heads until the test results were received by Farm Fresh Meats.




Evidence uncovered during the government's investigation established that Farm Fresh Meats and Farabee submitted samples from cattle outside the Targeted Cattle Population. Specifically, Farm Fresh Meats and Farabee submitted, or caused to be submitted, obex samples from healthy, USDA inspected cattle, in order to steal government moneys.




Evidence collected also demonstrated that Farm Fresh Meats and Farabee failed to maintain cattle carcasses and heads pending test results and falsified corporate books and records to conceal their malfeasance. Such actions, to the extent an obex sample tested positive (fortunately, none did), could have jeopardized the USDA's ability to identify the diseased animal and pinpoint its place of origin. On Wednesday, February 14, 2007, Farm Fresh Meats and Farabee pleaded guilty to stealing government funds and using the mails and wires to effect the scheme. According to their guilty pleas:




(a) Farm Fresh Meats collected, and Farabee directed others to collect, obex samples from cattle outside the Targeted Cattle Population, which were not subject to payment by the USDA;




(b) Farm Fresh Meats 2 and Farabee caused to be submitted payment requests to the USDA knowing that the requests were based on obex samples that were not subject to payment under the USDA Agreement;




(c) Farm Fresh Meats completed and submitted, and Farabee directed others to complete and submit, BSE Surveillance Data Collection Forms to the USDA's testing laboratory that were false and misleading;




(d) Farm Fresh Meats completed and submitted, and Farabee directed others to complete and submit, BSE Surveillance Submission Forms filed with the USDA that were false and misleading;




(e) Farm Fresh Meats falsified, and Farabee directed others to falsify, internal Farm Fresh Meats documents to conceal the fact that Farm Fresh Meats was seeking and obtaining payment from the USDA for obex samples obtained from cattle outside the Targeted Cattle Population; and




(f) Farm Fresh Meats failed to comply with, and Farabee directed others to fail to comply with, the USDA Agreement by discarding cattle carcasses and heads prior to receiving BSE test results. A conviction for theft of government funds carries a maximum penalty of 10 years imprisonment. Mail fraud and wire fraud convictions carry a maximum penalty of 20 years imprisonment. Convictions for the above referenced violations also carry a maximum fine of $250,000 for individuals and $500,000 for organizations. In determining an actual sentence, Judge Earl H. Carroll will consult the U.S. Sentencing Guidelines, which provide appropriate sentencing ranges. The judge, however, is not bound by those guidelines in determining a sentence.




Sentencing is set before Judge Earl H. Carroll on May 14, 2007. The investigation in this case was conducted by Assistant Special Agent in Charge Alejandro Quintero, United States Department of Agriculture, Office of Inspector General. The prosecution is being handled by Robert Long, Assistant U.S. Attorney, District of Arizona, Phoenix. CASE NUMBER: CR-07-00160-PHX-EHC RELEASE NUMBER: 2007-051(Farabee) # # #




http://www.usdoj.gov/usao/az/press_rele ... 51(Farabee).pdf


:welcome:


see full text ;


http://transmissiblespongiformencephalo ... -from.html


i know facts are difficult for some to digest, better facts than TSE prions though. ...


kind regards,
terry
 
Why don't you just come right out and state your mission flounder. It's come to my attention that you lost your mother to a variant of cjd.
I'm sorry for your loss. How do you feel she contracted it?
I'm All for testing where warranted, but you have taken a personal loss and made it your mission. Or should i say obsession? Let me tell you flat out....
Sometimes people die of a disease where there is no plausible Explanation that makes a darn but of sense. You can test till your blue in the face and still never understand why. I know because my wife was faced with a situation we couldn't explain why. But it was.
Maybe it's time for you to move forward and quit looking in the review mirror.
 
and flounder, your point posting all this stuff here is - why?

What are we supposed to do? Stop raising cattle?

Posting links to blogs where anyone can write anything and claim that it is true reminds me of the insurance commercial where the naive young woman states "you can't put anything on the Internet that isn't true."

Maybe it is time to get off of your soapbox here.

[youtube]rmx4twCK3_I[/youtube]

Edited to add: I am sorry about your Mother. I lost mine too and it can be difficult to move on.
 

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