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Covid - good news
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<blockquote data-quote="D2Cat" data-source="post: 1676900" data-attributes="member: 19322"><p>Here's some interesting information about past exposure and current effects.</p><p></p><p></p><p>Last July, as I was flipping through some recent</p><p>research publications, one particular paper</p><p>caught my attention.</p><p></p><p>A joint team of researchers from Duke and the</p><p>National University of Singapore published a</p><p>remarkable look at the immune system and how</p><p>effectively our bodies can build T cell immunity</p><p>to coronaviruses.</p><p></p><p>T cells (and B cells) are the types of white blood</p><p>cells that are critical to what is referred to as our</p><p>adaptive immune system. Our adaptive immune</p><p>system fights invading pathogens and other foreign</p><p>molecules using these T cells and B cells.</p><p></p><p>T cell receptors (TCRs) exist on the surface of our</p><p>T cells, and they are "programmed" to recognize</p><p>antigens, which are proteins that are produced as</p><p>a result of exposure to a virus or pathogen. That</p><p>way, if we have been exposed to a pathogen, our</p><p>bodies learn to recognize and fight off the disease</p><p>in the future.</p><p></p><p>Needless to say, the timing of the research was</p><p>highly relevant considering that it was only in</p><p>March of last year when the world came to terms</p><p>with the fact that COVID-19 (SARS-CoV-2) had</p><p>spread far and wide. (My italics)<em>This research should have</em></p><p><em>been disseminated widely, but it wasn't. Sadly, it</em></p><p><em>was largely ignored.</em></p><p><em></em></p><p><em>The research demonstrated that patients who</em></p><p><em>were exposed to SARS-CoV-1 during the SARS</em></p><p><em>outbreak in the early 2000s and recovered still</em></p><p><em>had T cell memory that reacted to exposure to</em></p><p><em>the same coronavirus over 17 years later. That's</em></p><p><em>right – almost two decades of natural immunity</em></p><p><em>and counting.</em></p><p></p><p>Ironically, while I wasn't part of the research, I</p><p>was actually one of those people exposed to the</p><p>virus. I was on a business trip in Hong Kong at</p><p>the absolute height of the SARS-CoV-1 outbreak</p><p>in 2003. I must have contracted the virus on that</p><p>trip, but I never knew it. I was asymptomatic, as</p><p>most people were.</p><p></p><p>It wasn't until I was tested a few months after I</p><p>caught COVID-19 last March that I realized I had</p><p>been exposed to both.</p><p></p><p>Interestingly, the research also demonstrated</p><p>that patients who had already been exposed to</p><p>SARS-CoV-1 demonstrated strong cross-reactivity</p><p>when exposed to COVID-19. Put more simply,</p><p>those patients' T cell immunity, developed</p><p>back in 2003 from SARS-CoV-1, protected them</p><p>against COVID-19.</p><p></p><p>Also surprising was that the research demonstrated</p><p>that preexisting T cell memory "learned"</p><p>from exposure to common cold coronaviruses</p><p>could cross-recognize COVID-19 down to the exact</p><p>molecular structure. That's right – exposure</p><p>to common cold coronaviruses actually helps</p><p>train our immune system to fight off COVID-19.</p><p></p><p>And that's why the majority of cases of COVID-19</p><p>go undetected. They are asymptomatic. And this</p><p>is also why many cases that do present symptoms</p><p>are mild and don't even require a visit to a doctor.</p><p></p><p><strong>The Crisis That Fueled Breakthroughs</strong></p><p></p><p>What a different year 2020 would have been if the</p><p>media and politicians had read and understood</p><p>this research. The fear and panic could have been</p><p>completely avoided. But sadly, the political narratives</p><p>won at great devastation and cost that we are</p><p>only now beginning to understand.</p><p></p><p>But something good has come out of all of this.</p><p>Not only have we seen incredible advancements</p><p>in messenger RNA (mRNA) technology used</p><p>to develop vaccines, the COVID-19 pandemic</p><p>has created a lot of awareness and excitement</p><p>around our immune systems.</p></blockquote><p></p>
[QUOTE="D2Cat, post: 1676900, member: 19322"] Here's some interesting information about past exposure and current effects. Last July, as I was flipping through some recent research publications, one particular paper caught my attention. A joint team of researchers from Duke and the National University of Singapore published a remarkable look at the immune system and how effectively our bodies can build T cell immunity to coronaviruses. T cells (and B cells) are the types of white blood cells that are critical to what is referred to as our adaptive immune system. Our adaptive immune system fights invading pathogens and other foreign molecules using these T cells and B cells. T cell receptors (TCRs) exist on the surface of our T cells, and they are “programmed” to recognize antigens, which are proteins that are produced as a result of exposure to a virus or pathogen. That way, if we have been exposed to a pathogen, our bodies learn to recognize and fight off the disease in the future. Needless to say, the timing of the research was highly relevant considering that it was only in March of last year when the world came to terms with the fact that COVID-19 (SARS-CoV-2) had spread far and wide. (My italics)[I]This research should have been disseminated widely, but it wasn’t. Sadly, it was largely ignored. The research demonstrated that patients who were exposed to SARS-CoV-1 during the SARS outbreak in the early 2000s and recovered still had T cell memory that reacted to exposure to the same coronavirus over 17 years later. That’s right – almost two decades of natural immunity and counting.[/I] Ironically, while I wasn’t part of the research, I was actually one of those people exposed to the virus. I was on a business trip in Hong Kong at the absolute height of the SARS-CoV-1 outbreak in 2003. I must have contracted the virus on that trip, but I never knew it. I was asymptomatic, as most people were. It wasn’t until I was tested a few months after I caught COVID-19 last March that I realized I had been exposed to both. Interestingly, the research also demonstrated that patients who had already been exposed to SARS-CoV-1 demonstrated strong cross-reactivity when exposed to COVID-19. Put more simply, those patients’ T cell immunity, developed back in 2003 from SARS-CoV-1, protected them against COVID-19. Also surprising was that the research demonstrated that preexisting T cell memory “learned” from exposure to common cold coronaviruses could cross-recognize COVID-19 down to the exact molecular structure. That’s right – exposure to common cold coronaviruses actually helps train our immune system to fight off COVID-19. And that’s why the majority of cases of COVID-19 go undetected. They are asymptomatic. And this is also why many cases that do present symptoms are mild and don’t even require a visit to a doctor. [B]The Crisis That Fueled Breakthroughs[/B] What a different year 2020 would have been if the media and politicians had read and understood this research. The fear and panic could have been completely avoided. But sadly, the political narratives won at great devastation and cost that we are only now beginning to understand. But something good has come out of all of this. Not only have we seen incredible advancements in messenger RNA (mRNA) technology used to develop vaccines, the COVID-19 pandemic has created a lot of awareness and excitement around our immune systems. [/QUOTE]
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