Menu
Forums
New posts
Search forums
What's new
New posts
New media
New media comments
New profile posts
Latest activity
Media
New media
New comments
Search media
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
What's new
Search
Search
Search titles and first posts only
Search titles only
By:
New posts
Search forums
Menu
Log in
Register
Forums
Cattle Boards
Breeds Board
Cloning
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Reply to thread
Help Support CattleToday:
Message
<blockquote data-quote="whitecow" data-source="post: 747667" data-attributes="member: 8638"><p>True that mitochondrial DNA is only passed on through the egg. Hence, it has no affect on male clones. There have been several studies looking at differences in mtDNA and very few have found any correlation to mtDNA sequences and any measureable traits. One study in dairy cattle did find an association between milk components and mtDNA but it is not clear that that correlation was not also associated with chromosomal genotype. Other differences that clones may have are associated with epigenetics (e.g., DNA methylation). The DNA methylation patterns of clones may be different than the original and different from each other. However, the next generation or the offspring of clones seem to have normal methylation patterns. My interest in cloning "248" was to get as many offspring out of her as I can. I expect they to be just as good as offspring from the original.</p><p></p><p>FWIW, 8 of my clones are peas in a pod. Even the position of the ovaries/uterus/broad ligament as heifers was identical. One heifer looks a bit different and her repro tract was a bit different. However, I expect her offspring will perform just as well as all the others.</p><p></p><p>George, M6 Ranch has a Charolais & Hereford bull sale tomorrow. They are also selling some show prospect heifers. Our place is about 10 miles south of M6.</p></blockquote><p></p>
[QUOTE="whitecow, post: 747667, member: 8638"] True that mitochondrial DNA is only passed on through the egg. Hence, it has no affect on male clones. There have been several studies looking at differences in mtDNA and very few have found any correlation to mtDNA sequences and any measureable traits. One study in dairy cattle did find an association between milk components and mtDNA but it is not clear that that correlation was not also associated with chromosomal genotype. Other differences that clones may have are associated with epigenetics (e.g., DNA methylation). The DNA methylation patterns of clones may be different than the original and different from each other. However, the next generation or the offspring of clones seem to have normal methylation patterns. My interest in cloning "248" was to get as many offspring out of her as I can. I expect they to be just as good as offspring from the original. FWIW, 8 of my clones are peas in a pod. Even the position of the ovaries/uterus/broad ligament as heifers was identical. One heifer looks a bit different and her repro tract was a bit different. However, I expect her offspring will perform just as well as all the others. George, M6 Ranch has a Charolais & Hereford bull sale tomorrow. They are also selling some show prospect heifers. Our place is about 10 miles south of M6. [/QUOTE]
Insert quotes…
Verification
Post reply
Forums
Cattle Boards
Breeds Board
Cloning
Top