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Health & Nutrition
Calf Reaction to IM Penicillin Injection
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<blockquote data-quote="Lucky_P" data-source="post: 1592799" data-attributes="member: 12607"><p>Very few cconditions that I'd even consider using penicillin for, anymore...we don't keep any on hand, haven't had any here in over 5 years.</p><p>Regardless of what's on the label, from a pharmacokinetic standpoint, the appropriate dose for procaine pen G is 3ml/100 lb body twice daily for 3 -5 days or longer.</p><p>'Long-acting' pen products are awful, and would not be approved if they had to go through the process today... the benzathine pen fraction that confers the 'long-acting' activity does stay in the animal longer, but it never attains a high enough blood/tissue level to kill ANYTHING. Add to that, the procaine pen G fraction is half that in the normal PPG injection product, and you've effectively underdosed the patient if you follow label dosage.</p><p>I'd bet a Coke that most animals treated with 'penicillin' by most CT members would have fared just as well if they'd received no antibiotic injection at all</p></blockquote><p></p>
[QUOTE="Lucky_P, post: 1592799, member: 12607"] Very few cconditions that I'd even consider using penicillin for, anymore...we don't keep any on hand, haven't had any here in over 5 years. Regardless of what's on the label, from a pharmacokinetic standpoint, the appropriate dose for procaine pen G is 3ml/100 lb body twice daily for 3 -5 days or longer. 'Long-acting' pen products are awful, and would not be approved if they had to go through the process today... the benzathine pen fraction that confers the 'long-acting' activity does stay in the animal longer, but it never attains a high enough blood/tissue level to kill ANYTHING. Add to that, the procaine pen G fraction is half that in the normal PPG injection product, and you've effectively underdosed the patient if you follow label dosage. I'd bet a Coke that most animals treated with 'penicillin' by most CT members would have fared just as well if they'd received no antibiotic injection at all [/QUOTE]
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Calf Reaction to IM Penicillin Injection
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