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Cattle Boards
Breeding / Calving Issues
Bull with translocation gene, semen testing questions
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<blockquote data-quote="inyati13" data-source="post: 1042821" data-attributes="member: 17767"><p>djinwa, I could not find reference to a "translocator gene". There may be some translocations that are influenced by a "translocator gene", but I could not find any. The translocation you are referencing, the (1;29) Robertsonian Translocation, does not appear to be influenced by a "translocator gene". </p><p></p><p>The origins of translocations in the life history of a line of cattle is a random occurrance. After that, the genetic defect becomes inherited. Italics, <em>the origination of translocations in this case a bull is during spermatogenesis, when the spermatozoa are being formed by the process of meiosis; the chromosomes line up and homologous chromosomes separate. When they separate, the limbs of the chromosomes can become broken and get mixed with a non-homologous chromosome (translocated). This is a random event.</em> Accident is not the word to use, call it a random anomaly.</p><p></p><p>After origination, the translocated genes become inherited by the off spring. The off-spring like this subject bull become carriers. There will be a predictable inheritance of the defect. The abstract to your second reference is more related to predicting fertility not the frequecy of the defects occurance. NOTE: Cows may also carry the (1;29).</p><p></p><p>The other thread on Translocation, I started for the purpose of determining what testing is performed. I called Select Sires and they directed me to the National Association of Animal Breeders (NAAB) which has a subsidiary, Certified Semen Service (CSS) that operates under an MOU with the USDA. There is not routine testing for genetic anomalies or for determining if animals are carriers of genetic defects. Semen companies may test based on their own inhouse protocols, for example, Kenley Conner stated that SS tests for CA, AM, and NH in the Black Angus breed.</p></blockquote><p></p>
[QUOTE="inyati13, post: 1042821, member: 17767"] djinwa, I could not find reference to a "translocator gene". There may be some translocations that are influenced by a "translocator gene", but I could not find any. The translocation you are referencing, the (1;29) Robertsonian Translocation, does not appear to be influenced by a "translocator gene". The origins of translocations in the life history of a line of cattle is a random occurrance. After that, the genetic defect becomes inherited. Italics, [i]the origination of translocations in this case a bull is during spermatogenesis, when the spermatozoa are being formed by the process of meiosis; the chromosomes line up and homologous chromosomes separate. When they separate, the limbs of the chromosomes can become broken and get mixed with a non-homologous chromosome (translocated). This is a random event.[/i] Accident is not the word to use, call it a random anomaly. After origination, the translocated genes become inherited by the off spring. The off-spring like this subject bull become carriers. There will be a predictable inheritance of the defect. The abstract to your second reference is more related to predicting fertility not the frequecy of the defects occurance. NOTE: Cows may also carry the (1;29). The other thread on Translocation, I started for the purpose of determining what testing is performed. I called Select Sires and they directed me to the National Association of Animal Breeders (NAAB) which has a subsidiary, Certified Semen Service (CSS) that operates under an MOU with the USDA. There is not routine testing for genetic anomalies or for determining if animals are carriers of genetic defects. Semen companies may test based on their own inhouse protocols, for example, Kenley Conner stated that SS tests for CA, AM, and NH in the Black Angus breed. [/QUOTE]
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