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Cattle Boards
Health & Nutrition
Booster Effectiveness ?
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<blockquote data-quote="Buck Randall" data-source="post: 1614174" data-attributes="member: 38590"><p>Cattle vaccinated with killed vaccine don't generally develop what we call "protective immunity". This means that they are still vulnerable to infection if challenged. However, their immune system does "remember" the vaccination and will respond faster than unvaccinated cattle would when exposed to a pathogen. In that case, the pathogen itself is serving as the booster. There hasn't been a lot of research into this (who would fund it?) but I've seen suggestions that this immune "memory" can last for years in some cases.</p><p></p><p>By the standards that the FDA sets for vaccine efficacy, unboosted killed vaccines provide zero coverage, but that doesn't mean that there is no value.</p></blockquote><p></p>
[QUOTE="Buck Randall, post: 1614174, member: 38590"] Cattle vaccinated with killed vaccine don't generally develop what we call "protective immunity". This means that they are still vulnerable to infection if challenged. However, their immune system does "remember" the vaccination and will respond faster than unvaccinated cattle would when exposed to a pathogen. In that case, the pathogen itself is serving as the booster. There hasn't been a lot of research into this (who would fund it?) but I've seen suggestions that this immune "memory" can last for years in some cases. By the standards that the FDA sets for vaccine efficacy, unboosted killed vaccines provide zero coverage, but that doesn't mean that there is no value. [/QUOTE]
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