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Angus Bulls with genetic defects
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<blockquote data-quote="DOC HARRIS" data-source="post: 223685" data-attributes="member: 1683"><p>alpha-mannosidosis is insidious and relates to the pH (power of the Hydrogen ion in cells and tissues) of Neural cells and systemic organs of the animal's body, and the explanation presented by Drs. Phillips, Robinson, Winchester and Jolly is clinically extensive and correct, and classically confusing! The bottom line is: if both copies of the gene are present - it is homozygous and lethal - and the calf dies shortly after birth! If only one copy of the gene is present, the calf, if it survives other vicissitudes of life, is heterozygous - and can be a carrier without manifesting the lethal trait and the calf's owner will not be aware of the gene's presence unless and until a DNA testing is performed - as with other Genetic traits and characteristics - or is mated with another carrier, and the "roll of the dice' produces a Homozygous progeny and we go back to square ONE!</p><p></p><p>My suggestion is this: DO NOT PANIC! The condition is not <em>contagious</em> as we consider epidemics and pandemics. I am convinced that the American Angus Association and our Veterinary Colleges and Drs. are on top of the problem as much as is possible at this point in time.</p><p></p><p>DOC HARRIS</p></blockquote><p></p>
[QUOTE="DOC HARRIS, post: 223685, member: 1683"] alpha-mannosidosis is insidious and relates to the pH (power of the Hydrogen ion in cells and tissues) of Neural cells and systemic organs of the animal's body, and the explanation presented by Drs. Phillips, Robinson, Winchester and Jolly is clinically extensive and correct, and classically confusing! The bottom line is: if both copies of the gene are present - it is homozygous and lethal - and the calf dies shortly after birth! If only one copy of the gene is present, the calf, if it survives other vicissitudes of life, is heterozygous - and can be a carrier without manifesting the lethal trait and the calf's owner will not be aware of the gene's presence unless and until a DNA testing is performed - as with other Genetic traits and characteristics - or is mated with another carrier, and the "roll of the dice' produces a Homozygous progeny and we go back to square ONE! My suggestion is this: DO NOT PANIC! The condition is not [i]contagious[/i] as we consider epidemics and pandemics. I am convinced that the American Angus Association and our Veterinary Colleges and Drs. are on top of the problem as much as is possible at this point in time. DOC HARRIS [/QUOTE]
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