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8,000 Years Progress = 50 Years Progress
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<blockquote data-quote="HerefordSire" data-source="post: 571262" data-attributes="member: 4437"><p>"This invention relates to the generation of animals including but not being limited to genetically selected and/or modified animals, and to cells useful in their generation. </p><p></p><p>The reconstruction of mammalian embryos by the transfer of a donor nucleus to an enucleated oocyte or one cell zygote allows the production of genetically identical individuals. This has clear advantages for both research (i.e. as biological controls) and also in commercial applications (i.e. multiplication of genetically valuable livestock, uniformity of meat products, animal management)........."</p><p></p><p></p><p></p><p>white cow...is this the patent your cloning protocol is based upon?</p><p></p><p>"A method of reconstituting an animal embryo involves transferring a diploid nucleus into an oocyte which is arrested in the metaphase of the second meiotic division. The oocyte is not activated at the time of transfer, so that the donor nucleus is kept exposed to the recipient cytoplasm for a period of time. The diploid nucleus can be donated by a cell in either the G0 or G1 phase of the cell cycle at the time of transfer. Subsequently, the reconstituted embryo is activated. Correct ploidy is maintained during activation, for example, by incubating the reconstituted embryo in the presence of a microtubule inhibitor such as nocodazole. The reconstituted embryo may then give rise to one or more live animal births. The invention is useful in the production of transgenic animals as well as non-transgenics of high genetic merit."</p><p></p><p></p><p><a href="http://www.uspto.gov/web/patents/patog/week17/OG/classification/classGroup_80.htm" target="_blank">http://www.uspto.gov/web/patents/patog/ ... oup_80.htm</a></p></blockquote><p></p>
[QUOTE="HerefordSire, post: 571262, member: 4437"] "This invention relates to the generation of animals including but not being limited to genetically selected and/or modified animals, and to cells useful in their generation. The reconstruction of mammalian embryos by the transfer of a donor nucleus to an enucleated oocyte or one cell zygote allows the production of genetically identical individuals. This has clear advantages for both research (i.e. as biological controls) and also in commercial applications (i.e. multiplication of genetically valuable livestock, uniformity of meat products, animal management)........." white cow...is this the patent your cloning protocol is based upon? "A method of reconstituting an animal embryo involves transferring a diploid nucleus into an oocyte which is arrested in the metaphase of the second meiotic division. The oocyte is not activated at the time of transfer, so that the donor nucleus is kept exposed to the recipient cytoplasm for a period of time. The diploid nucleus can be donated by a cell in either the G0 or G1 phase of the cell cycle at the time of transfer. Subsequently, the reconstituted embryo is activated. Correct ploidy is maintained during activation, for example, by incubating the reconstituted embryo in the presence of a microtubule inhibitor such as nocodazole. The reconstituted embryo may then give rise to one or more live animal births. The invention is useful in the production of transgenic animals as well as non-transgenics of high genetic merit." [url=http://www.uspto.gov/web/patents/patog/week17/OG/classification/classGroup_80.htm]http://www.uspto.gov/web/patents/patog/ ... oup_80.htm[/url] [/QUOTE]
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