i used some last year on some calves, heifers and older cows that i suspected of having coccidiosis. i had wormed them with valbazen thinking they had tapeworms (and some of them did i'm sure since ive found them in stool this year) and that had helped some of them a little bit but they were still in poor shape so i figured i'd mix some amprolium in their drinking water and see if it helped anything. i actually lost a bull calf to what i believe to be coccidiosis and his stool was so watery and clear that it looked like vaginal lube a cow puts out getting ready to calve. otheres passed what looked like blobs of mucus in their firmish stool while others had the watery manure. these cows and calves were also on rye grass and just not putting any weight on like they should be. anyway, it could have just been timing, or just taken them that long to get back into gaining weight mode after the worming, but within 2 weeks of the amprolium they were slick and shiney and fattening up. and i'm using it on a calf right now but i havent been using it long enough to really tell if its working on her but she looks a lot perkier. this is the time of year for coccidiosis to flare up. its expensive but if thats your problem it will be worth it. my vets around here arent much good with cows, they usually tell me my cows are just old when i have a problem. so i have to depend on trial and error alot, sometimes at the cows expense.