Around here leaving them and doing nothing results in blindness in that eye 90% of the time. We use the pen in the eyelid membrane like
@gcreekrch if it is a case that is "further along" like cloudy and looking rough; 2 cc pen with 1/2 cc dex for swelling...
I like to squirt some Today or Tomorrow mastitis medicine directly on the eyeball... it does not sting like the oxytets.. since it is made to use in the teat and not irritate the quarter of the cow.. The thicker "ointment" of the mastitis medicine seems to soothe the eye. We will patch them also; it helps to discourage flies, and it makes them not seek out dark/shaded spots as much.
The eyes get more sensitive to the sunlight when they are irritated for any reason... think about when you get something in your eye, the bright sun just seems to make it "hurt more" , so you squint or try to get out of bright light... same for the cows.
We also give them the "300" version of any brand oxytet (LA, Duramycin, etc).
Usually one treatment does it.
If it is just in the runny, beginning stage, just some Today or Tomorrow directly on the eyeball; usually we squirt it just under the eye lid so it spreads on the eye when they blink, will take care of it.
And let's face it, it is annoying and it "hurts" the cattle for their eyes to be runny and then to get that white color... it makes them often more skittish to work around if they get blind in one side and it is more dangerous for you to work them. Not fair to them to make them "suffer through" doing nothing if you can make it a little more comfortable for them while they have it...
We get a few with the white spots after they get over it, especially if it is a bad case...
Salt in the eye makes the eyes water more which was thought to "flush out" the eye more...
Damaged eyes, like with white spots or blind in one side, will often cause a lower price for the feeder calves. It won't make much difference in a mature cull animal, but the buyers do not pay as good most years for animals that have bad eyes. For that reason alone, treating them makes sense to not lose value of the feeder calf you are going to sell.
This year it does not seem to make as much of a difference with the frenzy of buyers wanting/needing feeders...
We have found that calves out of cattle that do not seem as susceptible to pinkeye here, are also more naturally resistant to getting it. I make notes about which calves would get it, and who they were out of...Nearly 80% of calves that seemed to get it were out of cows that we had bought, or their first generation heifers we kept for replacements. By the next generation, we saw few outbreaks. I think there is a factor of them building up resistance to it somewhat. We did not see anymore problems in hereford or crosses than with the angus... so the pink pigment around the eyes did not hold up here. Just my observations, not a "scientific study"....
We have a couple of bought cows, over the years, that got pinkeye when they came here... treated them and lost most/all the sight in an eye. They make good mothers and we are just considerate of the fact that you cannot try to work them/push them from the blind side. One raises a nice calf and we are very considerate of her when she is worked through the chute and such... some get more flighty when they lose some of their sight, but she is just calm and steady...