Charolais are bovines and ruminants, right? All cattle have essentially the same requirements for vaccinations, de-worming, etc. Most breeders vaccinate with a multi-spectrum vaccine (such as 4-Way, 7-Way, etc.) and for Brucellosis (Bangs). It is also recommended that any vaccination program include vaccines for STD's (Vibriosis and Leptospirosis). If your geographic area has problem with predators or varmits which carry rabies, then Rabies vaccination might be considered. Also, don't forget a regular de-worming and fly-control program. Most breeders vaccinate and de-worm in the Spring and Fall. Some also vaccinate cattle upon arrival to their facility (especially if the new arrivals don't have health records which accompany them. Texas and some other states have restrictions on interstate transportation of cattle without a negative TB test certification. If you have a bull that you lease out to others, is always a good idea to vaccinate him against STD's. Never know what the other "guys" are doing at their place or who their heifers and cows have been sleeping with...lol.