We have not used any insecticide for lice/parasites for 10 years. We run shaggy haired cattle in a cold northern climate - central alberta - using purebred Galloways, Highlands and a few Angus crosses for grass finished beef markets. We stopped using it for a few reasons.
1) My Mom became very ill just from the smell of it. For years she was the one who poured it on, and invariably got some on her skin. Over time she couldn't go near it without getting sick.
2) When I started paying my own way taking over the ranch I noticed some cows that had been missed in the fall with Ivomec did not lose any hair over the winter.
3) Curiosity kicked the be nice outta my kitty; I had to try it.
Here we are a decade later with no ill effects. The Galloways and Highlands don't seem to be bothered. Now before anyone runs out and buys a load of Galloway or Highland bulls( :lol: ) let me state my opinion - I don't believe that any single thing can be credited to insect resistance. Like anything else related to animal health, it is a whole systems approach. With the right balance of proper nutrition, good genetics and management, livestock can be expected to remain healthy AND productive without vaccinations, immunizations or antibiotics. The key for us has been the proper nutrition. We focus on our soils alot, and as they've improved, our pastures have improved, and our animals have improved.
The first couple years we saw some slick haired Angus cows that were never real thrifty, always had the reddish hair over the withers year round and such, lose hair in the fall and looked like they needed a shot of Ivomec to survive. We sold them in the first bred cow sale of the year and I'm sure they went on to be productive for someone else as long as they had that "crutch". The key is management and planning. Focus on the soil, and the forage and livestock have no excuse not to thrive. If they do not, get rid of them and SELECT for individuals that are better adapted to your eco-region. As the saying goes - a properly functioning endocrine system.