They need two Covexin 8 shots 4 to 6 weeks apart. At the time of castration, I give a tetanus antitoxin as a precaution. If they have had two Covexin 8 shots prior to castration, you are adequately covered. My vet does my castrations. I recently had two bull calves about 3 months old castrated. I told the vet they had their two Covexin 8 shots but I told him to hold them until I gave them an antitoxin. He said he didn't think the antitoxin was needed. I still gave it.Whatnow":12qg4ew8 said:Thanks Margonme! So with the Covexin 8, you don't give another tetanus shot after castration?